Chlorothiazide - Moligand™, 10mM in DMSO , Inhibitor of Na-Cl symporter, CAS No.58-94-6, Inhibitor of Na-Cl symporter

CAS: 58-94-6 Cat. No.: C408191 Formule: C₇H₆ClN₃O₄S₂ Poids moléculaire: 373.44 Numéro CE: 200-404-9

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

6-​chloro-​1,​1-​dioxide-2H-​1,​2,​4-​benzothiadiazine-​7-​sulfonamide

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Information

Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM)
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥98%

Specifications

Synonymes

6-​chloro-​1,​1-​dioxide-2H-​1,​2,​4-​benzothiadiazine-​7-​sulfonamide

Spécifications et pureté

Moligand™, 10mM in DMSO

Mécanismes biochimiques et physiologiques

Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM)

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Type d'action

INHIBITOR

Mécanisme d'action

Inhibitor of Na-Cl symporter

Noms et identifiants

• Isomères SMILES: C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)N=CN2
• Poids moléculaire: 373.44
• Reaxy-Rn: 1084805
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1084805&ln=

Cibles associées (humaines)

SLC12A3 Tclin Solute carrier family 12 member 3 (0 Activities)

Discover Target: SLC12A3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Références

1. Hongying Liu, Cairui Zhang, Chenwei Wang, Kai Fan, Yuqing Zhang, Lu Fang, Lihua Li, Chaoxiang Ren, Zheng-Zhi Yin, Zhong Lü.  (2023)  A highly selective and sensitive sensor for promethazine based on molecularly imprinted interface coated Au/Sn bimetal nanoclusters functionalized acupuncture needle microelectrode.  ANALYTICA CHIMICA ACTA,      [PMID:37290856] [10.1016/j.aca.2023.341395]

Foire aux questions

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 58-94-6, the molecular formula is C7H6ClN3O4S2, and the molecular weight is 373.44 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.