Clindamycin Phosphate - ≥96% , CAS No.24729-96-2

CAS: 24729-96-2 Cat. No.: C129914 Formule: C₁₈H₃₄ClN₂O₈PS Poids moléculaire: 504.96 Numéro CE: 246-433-0

QUALITÉ & PURETÉ ≥96%

Synonyms

NCGC00166320-01 | BDBM241975 | Clindamycin Phosphate (U-28508E) | CLINDAMYCIN PHOSPHATE COMPONENT OF VELTIN | CLINDAMYCIN PHOSPHATE IN DEXTROSE 5% | SR-01000076168-1 | AKOS008901431 | AS-12554 | CLINDAMYCIN 2-DIHYDROGEN PHOSPHATE [MI] | CLINDAMYCIN PHOSPH

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Vue d’ensemble

Clindamycin Phosphate is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM.

Clindamycin is a lincosamide antibiotic which is considered as a semisynthetic derivative of lincomycin. It is mainly used as an antimicrobial agent.

An antibiotic with anti-inflammatory properties.

Spécifications

Synonymes

NCGC00166320-01 | BDBM241975 | Clindamycin Phosphate (U-28508E) | CLINDAMYCIN PHOSPHATE COMPONENT OF VELTIN | CLINDAMYCIN PHOSPHATE IN DEXTROSE 5% | SR-01000076168-1 | AKOS008901431 | AS-12554 | CLINDAMYCIN 2-DIHYDROGEN PHOSPHATE [MI] | CLINDAMYCIN PHOSPH

Spécifications et pureté

≥96%

Mécanismes biochimiques et physiologiques

Clindamycin Phosphate (U-28508E) is an antibiotic with anti-inflammatory properties. The compound is a potent antibiotic against anaerobic and gram-positive bacteria. Studies show that Clindamycin associates with the 50S ribosomal subunit, which leads to

Conditions de stockage de stockage

Store at 2-8°C,Argon charged

Expédié en

Wet ice

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Pureté

≥96%

Propriétés du produit

ALogP

-1.2

Noms et identifiants

Pubchem Sid

504758802

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504758802

Sourires canoniques

CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)OP(=O)(O)O)O)O)C(C)Cl

IUPAC Name

[(2R,3R,4S,5R,6R)-6-[(1S,2S)-2-chloro-1-[[(2S,4R)-1-methyl-4-propylpyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyloxan-3-yl] dihydrogen phosphate

InChIKey

UFUVLHLTWXBHGZ-MGZQPHGTSA-N

INCHI

1S/C18H34ClN2O8PS/c1-5-6-10-7-11(21(3)8-10)17(24)20-12(9(2)19)15-13(22)14(23)16(18(28-15)31-4)29-30(25,26)27/h9-16,18,22-23H,5-8H2,1-4H3,(H,20,24)(H2,25,26,27)/t9-,10+,11-,12+,13+,14-,15+,16+,18+/m0/s1

Isomères SMILES

CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)OP(=O)(O)O)O)O)[C@H](C)Cl

WGK Allemagne

3

RTECS

GF2625000

Poids moléculaire

504.96

Reaxy-Rn

42193760

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=42193760&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Proline and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Proline and derivatives
• Alternative Parents: Alpha amino acid amides Thioglycosides Pyrrolidinecarboxamides Monoalkyl phosphates Oxanes N-alkylpyrrolidines Monosaccharides Monothioacetals Trialkylamines Secondary carboxylic acid amides Secondary alcohols 1,2-diols Sulfenyl compounds Oxacyclic compounds Azacyclic compounds Hydrocarbon derivatives Carbonyl compounds Organic oxides Organochlorides Alkyl chlorides Organopnictogen compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Proline or derivatives - Alpha-amino acid amide - Glycosyl compound - S-glycosyl compound - Pyrrolidine carboxylic acid or derivatives - Pyrrolidine-2-carboxamide - Monoalkyl phosphate - Monosaccharide - Organic phosphoric acid derivative - Oxane - Phosphoric acid ester - N-alkylpyrrolidine - Alkyl phosphate - Pyrrolidine - Monothioacetal - Tertiary aliphatic amine - Tertiary amine - Secondary carboxylic acid amide - Secondary alcohol - Carboxamide group - 1,2-diol - Azacycle - Organoheterocyclic compound - Oxacycle - Sulfenyl compound - Hydrocarbon derivative - Organonitrogen compound - Organochloride - Alcohol - Organohalogen compound - Organooxygen compound - Organosulfur compound - Organic oxygen compound - Carbonyl group - Amine - Alkyl chloride - Alkyl halide - Organic nitrogen compound - Organopnictogen compound - Organic oxide - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as proline and derivatives. These are compounds containing proline or a derivative thereof resulting from reaction of proline at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Soluble in water, and DMSO
• Rotation spécifique [α]: 122° (C=1,H2O)
• Point de fusion (°C): 114°C
• Poids moléculaire: 505.000 g/mol
• XLogP3: -1.200
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 9
• Exact Mass: 504.146 Da
• Monoisotopic Mass: 504.146 Da
• Topological Polar Surface Area: 174.000 Ų
• Heavy Atom Count: 31
• Formal Charge: 0
• Complexity: 658.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 9
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1