Clobetasol propionate - Moligand™, 10mM in DMSO , Glucocorticoid receptor agonist, CAS No.25122-46-7, Glucocorticoid receptor agonist

CAS: 25122-46-7 Cat. No.: C409015 Formule: C₂₅H₃₂ClFO₅ Poids moléculaire: 466.97 Numéro CE: 246-634-3

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

CGP9555, CCl 4725 | (11β,​16β)​-21-​chloro-​9-​fluoro-​11-​hydroxy-​16-​methyl-​17-​(1-​oxopropoxy)​-​pregna-​1,​4-​diene-​3,​20-​dione

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Information

Clobetasol propionate Clobetasol propionate (CGP9555, CCl 4725) is an anti-inflammatory corticosteroid used to treat various skin disorders.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonymes

CGP9555, CCl 4725 | (11β,​16β)​-21-​chloro-​9-​fluoro-​11-​hydroxy-​16-​methyl-​17-​(1-​oxopropoxy)​-​pregna-​1,​4-​diene-​3,​20-​dione

Spécifications et pureté

Moligand™, 10mM in DMSO

Mécanismes biochimiques et physiologiques

Clobetasol propionate (CGP9555, CCl 4725) is an anti-inflammatory corticosteroid used to treat various skin disorders.

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Type d'action

AGONIST

Mécanisme d'action

Glucocorticoid receptor agonist

Propriétés du produit

ALogP

3.8

Noms et identifiants

Isomères SMILES

CCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)CCl

WGK Allemagne

2

RTECS

TU3725000

Poids moléculaire

466.97

Reaxy-Rn

37811597

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=37811597&ln=

Cibles associées (humaines)

CYP3A4 Tclin Cytochrome P450 3A4 (1 Activities)

Discover Target: CYP3A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor (3 Activities)

Discover Target: NR3C1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP3A5 Tclin Cytochrome P450 3A5 (5 Activities)

Discover Target: CYP3A5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propriétés chimiques et physiques

• Rotation spécifique [α]: +99.0 °～ +103.0°(C=1,Dioxane)
• Point de fusion (°C): 196.0°C-200.0°C

Foire aux questions

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 25122-46-7, the molecular formula is C25H32ClFO5, and the molecular weight is 466.97 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.