Clonidine HCl - 10mM in DMSO , Adrenergic receptor alpha-2 agonist, CAS No.4205-91-8, Adrenergic receptor alpha-2 agonist

CAS: 4205-91-8 Cat. No.: C408668 Molecular Weight: 266.55 Beilstein Registry Number: 4163525 EC Number: 224-121-5 PubChem CID: 20179

GRADE & PURITY 10mM in DMSO

Synonyms

N-​(2,​6-​dichlorophenyl)​-​4,​5-​dihydro-1H-​imidazol-​2-​amine,hydrochloride (1:1)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Clonidine HCl is a direct-actingα2 adrenergicagonist with an ED50 of 0.02±0.01 mg/kg.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyms

N-​(2, ​6-​dichlorophenyl)​-​4, ​5-​dihydro-1H-​imidazol-​2-​amine, hydrochloride (1:1)

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Clonidine HCl is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

AGONIST

Mechanism of action

Adrenergic receptor alpha-2 agonist

Names and Identifiers

• Isomeric SMILES: C1CN=C(N1)NC2=C(C=CC=C2Cl)Cl.Cl
• WGK Germany: 3
• RTECS: NJ2490000
• PubChem CID: 20179
• UN Number: 2811
• Molecular Weight: 266.55
• Beilstein: 4163525
• Reaxy-Rn: 4163525

Chemical and Physical Properties

• Solubility: Solubility (25°C) In vitro DMSO: 34 mg/mL (198.65 mM); Water: Insoluble; Ethanol: Insoluble
• Melt Point(°C): 312°C

References

1. Zhiqin Liu, Yufeng Xu, Wei Liu, Lin Wang, Zhen Dong, Jianguo Zeng.  (2025)  Macleaya cordata protopine total alkaloids as potential treatment for diarrhoea: Mechanistic insights and target identification.  RESEARCH IN VETERINARY SCIENCE,      [PMID:40184723] [10.1016/j.rvsc.2025.105633]