CRANAD-2 - ≥95% , CAS No.1193447-34-5

CAS: 1193447-34-5 Cat. No.: C276131 Formule: C₂₃H₂₅BF₂N₂O₂ Poids moléculaire: 410.26 Numéro CE: 806-116-5

GRADE & PURITY ≥95%

Synonyms

CRANAD 2 | BDBM50598536 | 4,4'-((1E,1'E)-(2,2-difluoro-2H-1l3,3,2l4-dioxaborinine-4,6-diyl)bis(ethene-2,1-diyl))bis(N,N-dimethylaniline) | AKOS024458354 | CRANAD-2 | EX-A4805 | 1193447-34-5 | [4-[(2Z)-2-[6-[(E)-2-[4-(dimethylamino)phenyl]ethenyl]-2,2-difl

Storage

Protected from light,Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Vue d’ensemble

Shipped at 4°C. Store at -20°C. Store In the Dark. Store under desiccating conditions.

Specifications

Synonymes

CRANAD 2 | BDBM50598536 | 4,4'-((1E,1'E)-(2,2-difluoro-2H-1l3,3,2l4-dioxaborinine-4,6-diyl)bis(ethene-2,1-diyl))bis(N,N-dimethylaniline) | AKOS024458354 | CRANAD-2 | EX-A4805 | 1193447-34-5 | [4-[(2Z)-2-[6-[(E)-2-[4-(dimethylamino)phenyl]ethenyl]-2,2-difl

Spécifications et pureté

≥95%

Mécanismes biochimiques et physiologiques

Near-infrared (NIR) Amyloid-β fluorescent probe. Upon interacting with Amyloid-β aggregates displays a 70-fold increase in fluorescence intensity accompanied by a 90 nm blue shift from 805 to 715 nm. Demonstrates high affinity for amyloid-β aggregates

Conditions de stockage de stockage

Protected from light,Store at -20°C,Desiccated

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureté

≥95%

Noms et identifiants

Pubchem Sid

504772612

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504772612

Sourires canoniques

[B-]1(OC(=CC(=CC=C2C=CC(=[N+](C)C)C=C2)O1)C=CC3=CC=C(C=C3)N(C)C)(F)F

IUPAC Name

[4-[(2Z)-2-[6-[(E)-2-[4-(dimethylamino)phenyl]ethenyl]-2,2-difluoro-1,3-dioxa-2-boranuidacyclohex-5-en-4-ylidene]ethylidene]cyclohexa-2,5-dien-1-ylidene]-dimethylazanium

InChIKey

PVXQJYXODFZTBR-UHFFFAOYSA-N

INCHI

1S/C23H25BF2N2O2/c1-27(2)20-11-5-18(6-12-20)9-15-22-17-23(30-24(25,26)29-22)16-10-19-7-13-21(14-8-19)28(3)4/h5-17H,1-4H3

Isomères SMILES

[B-]1(OC(=C/C(=C/C=C2C=CC(=[N+](C)C)C=C2)/O1)/C=C/C3=CC=C(C=C3)N(C)C)(F)F

Poids moléculaire

410.26

Reaxy-Rn

19805444

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=19805444&ln=

Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Soluble in DMSO to 5 mM (with warming)
• Sensibilité: Moisture and lightsensitive