CVN424 - 10mM in DMSO , CAS No.2254706-21-1

CAS: 2254706-21-1 Cat. No.: C656045 Formule: C₂₄H₂₉F₂N₅O₃ Poids moléculaire: 473.52 Numéro CE: 192-146-8 PubChem CID: 137359492

QUALITÉ & PURETÉ 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

CVN424 is an orally active and selective GPR6 inverse agonist with a K i of 9.4 nM and an EC 50 of 38 nM. CVN424 is brain-penetrant and has the potential for Parkinson disease research

In Vitro

CVN424 (Compound 6i) has 265 fold and 68 fold selectivities over GPR3 and GPR12. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Ki: 9.4 nM (GPR6), EC50: 38 nM (GPR6)

Spécifications

Spécifications et pureté

10mM in DMSO

Mécanismes biochimiques et physiologiques

CVN424 is an orally active and selective GPR6 inverse agonist with a K i of 9.4 nM and an EC 50 of 38 nM. CVN424 is brain-penetrant and has the potential for Parkinson disease research.

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Noms et identifiants

Isomères SMILES

CC(=O)N1CCC2=C(C1)N=C(C(=N2)N3CCC(CC3)OC4=C(C=C(C=C4)F)F)N[C@@H]5CCOC5

CAS alternatif

2254706-21-1

PubChem CID

137359492

Poids moléculaire

473.52

Cibles associées (humaines)

GPR6 Tchem G-protein coupled receptor 6 (4 Activities)

Discover Target: GPR6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (2 Activities)

Discover Target: KCNH2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)