Cylindrospermopsin - Moligand™,≥95% , CAS No.143545-90-8

CAS: 143545-90-8 Cat. No.: C329512 Molecular Weight: 415.42 EC Number: 802-929-4

GRADE & PURITY Moligand™, ≥95%

Synonyms

J-007833 | MLS002320509 | SMR001338799 | Q3008693 | (2aS,3R,4S,5aS,7R)-7-[(S)-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)(hydroxy)methyl]-3-methyl-2a,3,4,5,5a,6,7,8-octahydro-2H-1,8,8b-triazaacenaphthylen-4-yl hydrogen sulfate | 6-[(R)-Hydroxy[(2aS,3R,4S

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Tricyclic alkaloid hepatotoxin from a cyanobacterium.Cylindrospermopsin (abbreviated to CYN, or CYL) is a cyanotoxin produced by a variety of freshwater cyanobacteria. CYL is a polycyclic uracil derivative containing guanidino and sulfate groups. It is also zwitterionic, making it highly water soluble. CYL is toxic to liver and kidney tissue and is thought to inhibit protein synthesis and to covalently modify DNA and/or RNA.

Specifications

Synonyms

J-007833 | MLS002320509 | SMR001338799 | Q3008693 | (2aS, 3R, 4S, 5aS, 7R)-7-[(S)-(2, 6-dioxo-1, 2, 3, 6-tetrahydropyrimidin-4-yl)(hydroxy)methyl]-3-methyl-2a, 3, 4, 5, 5a, 6, 7, 8-octahydro-2H-1, 8, 8b-triazaacenaphthylen-4-yl hydrogen sulfate | 6-[(R)-Hydroxy[(2aS, 3R, 4S

Specifications & Purity

Moligand™, ≥95%

Source

Isolated from Cylindrospermopsis raciborskii.

Storage

Protected from light, Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Purity

≥95%

Product Properties

• pKa: pKₐ: -3.79 (Predicted), pKₐ: 15 (Predicted)

Names and Identifiers

• Isomeric SMILES: C[C@H]1[C@H](C[C@@H]2C[C@@H](NC3=NC[C@H]1N23)[C@H](C4=CC(=O)NC(=O)N4)O)OS(=O)(=O)O
• RTECS: UV9104310
• Molecular Weight: 415.42
• Reaxy-Rn: 28473372
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=28473372&ln=

Chemical and Physical Properties

• Solubility: Soluble in water, methanol, and DMSO.
• Sensitivity: Light sensitive
• Refractive Index: n20D1.86 (Predicted)

References

1. Long Wu, Luyao Jiao, Danni Xue, Yueqing Li, Yu Han, Wei Ouyang, Qi Chen.  (2024)  Nanozyme and bifunctional nanobody-based colorimetric-SERS dual-mode Immunosensor for microcystin-LR detection.  FOOD CHEMISTRY,      [PMID:39396471] [10.1016/j.foodchem.2024.141574]

2. Wei Zeng, Mingrui Lu, Long Wu, Xin Gao, Qi Chen, Sihang Zhang.  (2025)  Nanozyme mediated Raman-NLISA dual-modal immunosensor for accurate and sensitive detection of microcystin-LR.  FOOD CHEMISTRY,      [PMID:40311568] [10.1016/j.foodchem.2025.144480]