Determine the necessary mass, volume, or concentration for preparing a solution.
DB0614 , CAS No.2769753-47-9
DISPONIBLE À COMMANDE
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Application
PROTAC
DB0614 (Example 21) is a bifunctional compound targeted protein degradation of kinases. DB0614 degrades AAK1 , AURKA, BMP2K, CAMKK1, CDK16 , CML, CDK6 , EIF2AK2, FER, GAK, LCK, LIMK2 , MAP3KH, MAPK8, MAPK9, NEK9, PLK4 , PTK2B, SIK2 , STK17A, STK17B, ULK1 , ULK3, and WEE1 . DB0614 can be used for research of disease or disorder mediated by aberrant kinase activity
IC50& Target:CDK6 CDK16/Cyclin Y ULK1 Aurora Kinase SIK2 LIMK2