≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Conserver à -20°C Ships Glacière + blocs de glace Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
application：
Le DEL 22379 est un produit chimique utile pour la recherche. Le DEL 22379 a été utilisé pour la préparation d'inhibiteurs hydrosolubles de la 3-arylidène-2-oxyindole tyrosine kinase.
description du produit
Le DEL-22379 est un inhibiteur de la dimérisation de l'ERK. Le DEL-22379 se lie facilement à ERK2 avec un Kd estimé dans la plage micromolaire basse, bien que la liaison soit détectable même à de faibles concentrations nanomolaires. La dimérisation d'ERK2 est progressivement inhibée avec une CI50 d'environ 0,5 μM.
| Pubchem Sid | 504766180 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504766180 |
| Sourires canoniques | COC1=CC2=C(C=C1)NC=C2C=C3C4=C(C=CC(=C4)NC(=O)CCN5CCCCC5)NC3=O |
| IUPAC Name | N-[(3Z)-3-[(5-methoxy-1H-indol-3-yl)methylidene]-2-oxo-1H-indol-5-yl]-3-piperidin-1-ylpropanamide |
| InChIKey | INQUULPXCZAKMS-XKZIYDEJSA-N |
| INCHI | 1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21)29-26(22)32)28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2,1H3,(H,28,31)(H,29,32)/b22-13- |
| Isomères SMILES | COC1=CC2=C(C=C1)NC=C2/C=C\3/C4=C(C=CC(=C4)NC(=O)CCN5CCCCC5)NC3=O |
| Poids moléculaire | 444.53 |
| Reaxy-Rn | 18638308 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18638308&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Classe | Carboxylic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Intermediate Tree Nodes | Amino acids and derivatives |
| Direct Parent | Beta amino acids and derivatives |
| Alternative Parents | Indoles Indolines Anisoles N-arylamides Alkyl aryl ethers Substituted pyrroles Piperidines Heteroaromatic compounds Trialkylamines Secondary carboxylic acid amides Lactams Azacyclic compounds Organic oxides Organopnictogen compounds Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Beta amino acid or derivatives - Indole - Dihydroindole - Indole or derivatives - Anisole - N-arylamide - Alkyl aryl ether - Piperidine - Substituted pyrrole - Benzenoid - Pyrrole - Heteroaromatic compound - Tertiary aliphatic amine - Tertiary amine - Lactam - Secondary carboxylic acid amide - Carboxamide group - Ether - Azacycle - Organoheterocyclic compound - Amine - Hydrocarbon derivative - Organic nitrogen compound - Organic oxide - Carbonyl group - Organopnictogen compound - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as beta amino acids and derivatives. These are amino acids having a (-NH2) group attached to the beta carbon atom. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Article |
|---|---|---|---|
 K2526101 | Certificate of Analysis | Dec 10, 2025 | D288623 |
| J2130388 | Certificate of Analysis | Aug 14, 2024 | D288623 |
| J2130389 | Certificate of Analysis | Aug 14, 2024 | D288623 |
| J2130390 | Certificate of Analysis | Aug 14, 2024 | D288623 |
| J2130504 | Certificate of Analysis | Aug 14, 2024 | D288623 |
| Solubilité | Solvent:DMSO, Max Conc. mg/mL: 22.23, Max Conc. mM: 50 |
|---|---|
| Poids moléculaire | 444.500 g/mol |
| XLogP3 | 3.000 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 6 |
| Exact Mass | 444.216 Da |
| Monoisotopic Mass | 444.216 Da |
| Topological Polar Surface Area | 86.500 Ų |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 750.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 1 |
