Dexamethasone Solution (10mM) - BioReagent, for Cell culture, Sterile, 10 mM in DMSO , CAS No.50-02-2

CAS: 50-02-2 Cat. No.: C1524668 Formule: C₂₂H₂₉FO₅ Poids moléculaire: 392.46 Beilstein Registry Number: 2066651 Numéro CE: 200-003-9

QUALITÉ & PURETÉ BioReagent, for Cell culture, Sterile, 10 mM in DMSO

Synonyms

Dexamethasone Solution | DEX | DXM

Storage

Store at 2-8°C,Do not freeze

Shipped In

Wet ice

Vue d’ensemble

Dexamethasone is an adrenocortical hormone substance with multiple pharmacological effects including anti‑inflammatory, anti‑allergic, immunosuppressive and anti‑shock activities. It exerts certain physiological effects on cell culture, cell signal transduction and gene expression. Dexamethasone can induce disorder of hepatic glucose and lipid metabolism; inhibit the activation of the PI3K/Akt pathway and trigger osteoblast apoptosis; elevate intracellular ROS levels and mitochondrial superoxide production. It also induces the differentiation of human mesenchymal stem cells (MSCs), triggers autophagy in B‑cell acute lymphoblastic leukemia (B‑ALL), down‑regulates activated NF‑κB levels in immature dendritic cells (DCs), and suppresses their differentiation into mature DCs.

Dexamethasone Solution is a cell‑culture‑grade 10 mM stock solution. Researchers may dilute it at an appropriate ratio according to experimental requirements prior to direct use.

Product Properties:

CAS NO.: 50‑02‑2

Formula: C₂₂H₂₉FO₅

Molecular weight: 392.461

Appearance: Colorless transparent solution

Solubility: Soluble in ethanol and DMSO, slightly soluble in water

Melting point: 255～264 °C

Structure:

Precautions:

1. For your safety and health, please wear a lab coat and disposable gloves during operation.

2. This reagent is for research use only.

Spécifications

Synonymes

Dexamethasone Solution | DEX | DXM

Spécifications et pureté

BioReagent, for Cell culture, Sterile, 10 mM in DMSO

Stabilité et stockage

Store at 2-8°C long term (24 months). Store in the dark.

Conditions de stockage de stockage

Store at 2-8°C,Do not freeze

Expédié en

Wet ice

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

BioReagent, Les stériles, pour la culture cellulaire

Product Line

Produits biologiques

Propriétés du produit

ALogP

1.9

Noms et identifiants

Isomères SMILES

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C

WGK Allemagne

2

RTECS

TU3980000

CAS alternatif

23495-06-9,50-02-2

Numéro NSC

34521

Termes d'entrée MeSH

Decaject;Decaject L.A.;Decaject-L.A.;Decameth;Decaspray;Dexamethasone;Dexasone;Dexpak;Hexadecadrol;Hexadrol;Maxidex;Methylfluorprednisolone;Millicorten;Oradexon

Poids moléculaire

392.46

Beilstein

2066651

Reaxy-Rn

2341697

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2341697&ln=

Propriétés chimiques et physiques

• Solubilité: Soluble in ethanol and DMSO, slightly soluble in water
• Point de fusion (°C): 262-264°C