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· · COA & SDS available for every product · Same-day shipping on in-stock items Dianicline - ≥98%(HPLC) , Neuronal acetylcholine receptor; alpha4/beta2 partial agonist, CAS No.292634-27-6, Neuronal acetylcholine receptor; alpha4/beta2 partial agonist
Synonyms
Y0SNM34C6O | SSR591813L | SCHEMBL2354672 | Dianicline dihydrochloride | Q5271647 | UNII-Y0SNM34C6O | (1R,10S)-9-oxa-4,13-diazatetracyclo[11.2.1.01,10.03,8]hexadeca-3(8),4,6-triene | (5aS,10aR)-6,7,9,10-Tetrahydro-5aH,11H-8,10a-methanopyrido(2',3':5,6)pyra
Shipped In
Ice chest + Ice pads
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Why this grade ≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
Y0SNM34C6O | SSR591813L | SCHEMBL2354672 | Dianicline dihydrochloride | Q5271647 | UNII-Y0SNM34C6O | (1R, 10S)-9-oxa-4, 13-diazatetracyclo[11.2.1.01, 10.03, 8]hexadeca-3(8), 4, 6-triene | (5aS, 10aR)-6, 7, 9, 10-Tetrahydro-5aH, 11H-8, 10a-methanopyrido(2', 3':5, 6)pyra
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
Selectiveα4β2 nAChR partial agonist (IC50= 105 nM). Exhibits >20-fold selectivity forα4β2 over other nAChR subtypes. Increases dopamine turnover in rat nucleus accumbensin vivo. Orally bioavailable.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
PARTIAL AGONIST
Mechanism of action
Neuronal acetylcholine receptor; alpha4/beta2 partial agonist
Product Properties Names and Identifiers Canonical Smiles C1CN2CCC3(C2)C1OC4=C(C3)N=CC=C4 IUPAC Name (1R,10S)-9-oxa-4,13-diazatetracyclo[11.2.1.01,10.03,8]hexadeca-3(8),4,6-triene InChIKey SUPRUPHAEXPGPF-QWHCGFSZSA-N INCHI 1S/C13H16N2O/c1-2-11-10(14-5-1)8-13-4-7-15(9-13)6-3-12(13)16-11/h1-2,5,12H,3-4,6-9H2/t12-,13+/m0/s1 Isomeric SMILES C1CN2CC[C@@]3(C2)[C@H]1OC4=C(C3)N=CC=C4 Molecular Weight 289.2 Reaxy-Rn 14144545 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14144545&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Pyranopyridines Subclass Not available Intermediate Tree Nodes Not available Direct Parent Pyranopyridines Alternative Parents Azepanes Aralkylamines Alkyl aryl ethers Pyridines and derivatives Piperidines N-alkylpyrrolidines Heteroaromatic compounds Trialkylamines Oxacyclic compounds Azacyclic compounds Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents Pyranopyridine - Alkyl aryl ether - Azepane - Aralkylamine - Piperidine - Pyridine - N-alkylpyrrolidine - Heteroaromatic compound - Pyrrolidine - Tertiary aliphatic amine - Tertiary amine - Ether - Oxacycle - Azacycle - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Organic oxygen compound - Hydrocarbon derivative - Amine - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as pyranopyridines. These are polycyclic aromatic compounds containing a pyran ring fused to a pyridine ring. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:water, Max Conc. mg/mL: 28.92, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 5.78, Max Conc. mM: 20 Molecular Weight 216.280 g/mol XLogP3 1.400 Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 0 Exact Mass 216.126 Da Monoisotopic Mass 216.126 Da Topological Polar Surface Area 25.400 Ų Heavy Atom Count 16 Formal Charge 0 Complexity 296.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 2 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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