Doxylamine Succinate - 10mM in DMSO , Histamine H1 receptor antagonist, CAS No.562-10-7, Histamine H1 receptor antagonist

CAS: 562-10-7 Cat. No.: D424761 Formule: C₁₇H₂₂N₂O·C₄H₆O₄ Poids moléculaire: 388.46 Numéro CE: 209-228-7

QUALITÉ & PURETÉ 10mM in DMSO

Synonyms

Doxylamine succinate|562-10-7|Decapryn|Gittalun|Unisom|Hoggar N|Doxylamine (succinate)|Doxylamine succinate salt|Doxy-sleep-aid|Evigoa D|Decapryn Succinate|Doxylamine hydrogen succinate|Alsadorm|Mereprine|Sedaplus|A-H Injection|Doxylamine succinate (1:1)|

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Doxylamine succinate competitively inhibits histamine at H1 receptors with substantial sedative and anticholinergic effects

Spécifications

Synonymes

Doxylamine succinate | 562-10-7 | Decapryn | Gittalun | Unisom | Hoggar N | Doxylamine (succinate) | Doxylamine succinate salt | Doxy-sleep-aid | Evigoa D | Decapryn Succinate | Doxylamine hydrogen succinate | Alsadorm | Mereprine | Sedaplus | A-H Injection | Doxylamine succinate (1:1) |

Spécifications et pureté

10mM in DMSO

Mécanismes biochimiques et physiologiques

Doxylamine Succinate is an antihistaminic, sedative, and hypnotic. Doxylamine Succinate is also a H1 histamine receptor antagonist.

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

ANTAGONIST

Mécanisme d'action

Histamine H1 receptor antagonist

Noms et identifiants

Pubchem Sid

528771237

Sourires canoniques

CC(C1=CC=CC=C1)(C2=CC=CC=N2)OCCN(C)C.C(CC(=O)O)C(=O)O

IUPAC Name

butanedioic acid;N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine

InChIKey

KBAUFVUYFNWQFM-UHFFFAOYSA-N

INCHI

1S/C17H22N2O.C4H6O4/c1-17(20-14-13-19(2)3,15-9-5-4-6-10-15)16-11-7-8-12-18-16;5-3(6)1-2-4(7)8/h4-12H,13-14H2,1-3H3;1-2H2,(H,5,6)(H,7,8)

Isomères SMILES

CC(C1=CC=CC=C1)(C2=CC=CC=N2)OCCN(C)C.C(CC(=O)O)C(=O)O

WGK Allemagne

2

RTECS

US9275000

Poids moléculaire

388.46

Reaxy-Rn

3829474

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3829474&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Benzylethers

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Benzylethers
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzylethers
• Alternative Parents: Pyridines and derivatives Dicarboxylic acids and derivatives Heteroaromatic compounds Trialkylamines Dialkyl ethers Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Not available
• Substituents: Benzylether - Dicarboxylic acid or derivatives - Pyridine - Heteroaromatic compound - Tertiary aliphatic amine - Tertiary amine - Azacycle - Organoheterocyclic compound - Ether - Dialkyl ether - Amine - Organopnictogen compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as benzylethers. These are aromatic ethers with the general formula ROCR' (R = alkyl, aryl; R'=benzene).
• External Descriptors: organic molecular entity

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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Mécanismes d'action

Propriétés chimiques et physiques

• Sensibilité: Light sensitive
• Point de fusion (°C): 95-98°C
• Poids moléculaire: 388.500 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 9
• Exact Mass: 388.2 Da
• Monoisotopic Mass: 388.2 Da
• Topological Polar Surface Area: 100.000 Ų
• Heavy Atom Count: 28
• Formal Charge: 0
• Complexity: 369.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3