10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Duloxetine HCl Duloxetine HCl (LY-248686) is a serotonin-norepinephrine reuptake inhibitor with K i of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).
In vitro
In vivo
Cell Data
cell lines：CAL-62 cells
Concentrations：
Incubation Time：
Powder Purity:≥99%
| Isomères SMILES | CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=CC=CC=C32.Cl |
|---|---|
| WGK Allemagne | 3 |
| RTECS | XN0258000 |
| CAS alternatif | 116817-13-1 |
| Poids moléculaire | 333.88 |
| Reaxy-Rn | 13592284 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13592284&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Indice de réfraction | 122° (C=1,MeOH) |
|---|---|
| Rotation spécifique [α] | 122° (C=1,MeOH) |
| Point de fusion (°C) | 164℃ |
| 1. Weijun Zhou, Wenyun Zhou, Yonghao Bi, Zibin Zhou, Zhigao Zhou, Shaozhe Chen, Gang Xie, Zhen Lian, Guixin Yuan, Guanfeng Yao. (2023) Antidepressant duloxetine hydrochloride protects against ovariectomy-induced bone loss in mice by inhibiting osteoclast differentiation. BIOMEDICINE & PHARMACOTHERAPY, [PMID:37913736] [10.1016/j.biopha.2023.115810] |
| 2. Jingjing Chen, Peipei Li, Yixiu Han, Yuchen Li, Yingxiang Du. (2023) Highly photoluminescent nitrogen-doped carbon quantum dots as a green fluorescence probe for determination of myricetin. FOOD CHEMISTRY, [PMID:36933427] [10.1016/j.foodchem.2023.135920] |
| 3. Xiujuan Chen, Chen Liang, Lijun Cui, Jian Le, Zheyuan Qian, Runsheng Zhang, Zhanying Hong, Yifeng Chai. (2018) A rapid LC-MS/MS method for simultaneous determination of quetiapine and duloxetine in rat plasma and its application to pharmacokinetic interaction study. JOURNAL OF FOOD AND DRUG ANALYSIS, [PMID:30648587] [10.1016/j.jfda.2018.07.003] |
| 4. Rikun Cui, Zhenzhao Wang, Linna Li, Lili Liu, Zhen Li, Xingtong Liu, Tingting Chen, Ayesha Rauf, Xiaofeng Kang, Yanli Guo. (2024) Bionic nanopore recognition receptors for single-molecule enantioselectivity studies of chiral drugs. ANALYTICA CHIMICA ACTA, [PMID:39067929] [10.1016/j.aca.2024.342960] |
