Dynapyrazole A - ≥98%(HPLC) , CAS No.2226517-75-3

CAS: 2226517-75-3 Cat. No.: D286580 Formule: C₂₀H₁₂ClIN₄O Poids moléculaire: 486.7

GRADE & PURITY ≥98%(HPLC)

Synonyms

2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Synonymes

2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile

Spécifications et pureté

≥98%(HPLC)

Mécanismes biochimiques et physiologiques

Dynein inhibitor. Inhibits dynein 1 and dynein 2-dependent microtubule gliding (IC50values are 2.3 and 2.6 μM, respectively). Inhibits hedgehog signalingin vitro(IC50= 1.9 μM). Displays reversible inhibition of retrograde and anterograde intraflagellar tr

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Pureté

≥98%(HPLC)

Noms et identifiants

Pubchem Sid

504773463

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504773463

Sourires canoniques

C1CC1(C2=CC=C(C=C2)Cl)C3=NN4C5=C(C=C(C=C5)I)C(=O)NC4=C3C#N

IUPAC Name

2-[1-(4-chlorophenyl)cyclopropyl]-7-iodo-5-oxo-4H-pyrazolo[1,5-a]quinazoline-3-carbonitrile

InChIKey

VABPBCMFKJDOHP-UHFFFAOYSA-N

INCHI

1S/C20H12ClIN4O/c21-12-3-1-11(2-4-12)20(7-8-20)17-15(10-23)18-24-19(27)14-9-13(22)5-6-16(14)26(18)25-17/h1-6,9H,7-8H2,(H,24,27)

Poids moléculaire

486.7

Reaxy-Rn

31360567

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=31360567&ln=

Propriétés chimiques et physiques

• Solubilité: Solvent:DMSO, Max Conc. mg/mL: 9.73, Max Conc. mM: 20

Foire aux questions

What is the purity of this product, and how is it determined?

This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2226517-75-3, the molecular formula is C20H12ClIN4O, and the molecular weight is 486.7 g/mol. InChIKey VABPBCMFKJDOHP-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.