Eaton′s Reagent - P2O5 ca 7.5% w/w , CAS No.39394-84-8

CAS: 39394-84-8 Cat. No.: E140657 EC Number: 679-375-3

GRADE & PURITY P2O5 ca 7.5% w/w

Synonyms

Methanesulfonic acid--3-oxo-1lambda~5~,3lambda~5~-diphosphoxane-1,1,3-trione (1/1) | D78003 | methanesulfonic acid compound with phosphenic anhydride (1:1) | AKOS027469870 | Eaton's Reagent | Phosphorus pentoxide methanesulfonic acid | eaton'S | MFCD00070

Storage

Room temperature,Argon charged,Desiccated,Cool

Shipped In

Normal

Specifications

Synonyms

Methanesulfonic acid--3-oxo-1lambda~5~, 3lambda~5~-diphosphoxane-1, 1, 3-trione (1/1) | D78003 | methanesulfonic acid compound with phosphenic anhydride (1:1) | AKOS027469870 | Eaton's Reagent | Phosphorus pentoxide methanesulfonic acid | eaton'S | MFCD00070

Specifications & Purity

P2O5 ca 7.5% w/w

Storage

Room temperature, Argon charged, Desiccated, Cool

Shipped In

Normal

Names and Identifiers

• Canonical Smiles: CS(=O)(=O)O.O=P(=O)OP(=O)=O
• InChIKey: JHNLZOVBAQWGQU-UHFFFAOYSA-N
• INCHI: 1S/CH4O3S.O5P2/c1-5(2,3)4;1-6(2)5-7(3)4/h1H3,(H,2,3,4)
• Isomeric SMILES: CS(=O)(=O)O.O=P(=O)OP(=O)=O
• WGK Germany: 1
• UN Number: 1760
• Packing Group: II
• Reaxy-Rn: 20559020
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20559020&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Organic sulfonic acids and derivatives
      • Subclass Organosulfonic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Organic sulfonic acids and derivatives
• Subclass: Organosulfonic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Organosulfonic acids
• Alternative Parents: Sulfonyls Methanesulfonates Alkanesulfonic acids Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alkanesulfonic acid - Sulfonyl - Organosulfonic acid - Methanesulfonate - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organosulfur compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as organosulfonic acids. These are compounds containing the sulfonic acid group, which has the general structure RS(=O)2OH (R is not a hydrogen atom).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Decomposes in water.
• Sensitivity: Moisture Sensitive.
• Refractive Index: 1.435
• Flash Point(°F): 230°F
• Flash Point(°C): >110°C
• Boil Point(°C): 122 °C/1 mmHg
• Molecular Weight: 238.050 g/mol
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 0
• Exact Mass: 237.91 Da
• Monoisotopic Mass: 237.91 Da
• Topological Polar Surface Area: 140.000 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 216.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

1. Hui Yao, Qiaoqin Fu, Yuchen Zhang, Ying Wan, Qing Min.  (2023)  Strong, elastic and degradation-tolerated hydrogels composed of chitosan, silk fibroin and bioglass nanoparticles with factor-bestowed activity for bone tissue engineering.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:37657578] [10.1016/j.ijbiomac.2023.126619]

2. Yingying Huang, Lihui Tan, Meng Chen, Yanpeng Jiao, Jinhuan Tian, Lihua Li, Changren Zhou, Lu Lu.  (2022)  Laccase immobilization on hierarchical micro/nano porous chitin/graphene oxide beads prepared via Pickering emulsion template for dye decolorization.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2022.130858]

3. Yuhong Huang, Xiaowei Li, Linlin Chen, Guiling Luo, Duanjian Tao, Jing Sun, Zhenjiang Qiu, Yanhong Chao, Wenshuai Zhu.  (2022)  Synthesis of a magnetic crown ether ion imprinted polymer material for the selective adsorption of lithium.  NEW JOURNAL OF CHEMISTRY,  47  (6): (3134-3139).  [PMID:] [10.1039/D2NJ05377B]

4. Jianwei Zhao, Yuxin Wang, Dezheng Guan, Zhou Fu, Qi Zhang, Liang Guo, Yingjie Sun, Qiuzhuo Zhang, Dongbo Wang.  (2022)  Calcium hypochlorite-coupled aged refuse promotes hydrogen production from sludge anaerobic fermentation.  BIORESOURCE TECHNOLOGY,      [PMID:36574889] [10.1016/j.biortech.2022.128534]

5. Kaibo Yu, Jing Xu, Lei Zhou, Liqiang Zou, Wei Liu.  (2021)  Effect of Chitosan Coatings with Cinnamon Essential Oil on Postharvest Quality of Mangoes.  Foods,  10  (12): (3003).  [PMID:34945553] [10.3390/foods10123003]

6. Zhiquan Chen, Juncheng Jiang, Yuan Yu, Gang Chen, Tingting Chen, Qingwu Zhang.  (2020)  Layer-by-layer assembled bagasse to enhance the fire safety of epoxy resin: A renewable environmental friendly flame retardant.  JOURNAL OF APPLIED POLYMER SCIENCE,  138  (11): (50032).  [PMID:] [10.1002/app.50032]

7. Qiufeng Lin, Feilong Dong, Yunxia Miao, Cong Li, Weicheng Fei.  (2019)  Removal of disinfection by-products and their precursors during drinking water treatment processes.  WATER ENVIRONMENT RESEARCH,  92  (5): (698-705).  [PMID:31643120] [10.1002/wer.1263]

8. Qing Min, Xiaofeng Yu, Jiaoyan Liu, Jiliang Wu, Ying Wan.  (2019)  Chitosan-Based Hydrogels Embedded with Hyaluronic Acid Complex Nanoparticles for Controlled Delivery of Bone Morphogenetic Protein-2.  Pharmaceutics,  11  (5): (214).  [PMID:31060227] [10.3390/pharmaceutics11050214]

9. Hao-Hua Deng, Xiu-Ling Lin, Yin-Huan Liu, Ke-Lin Li, Qiong-Qiong Zhuang, Hua-Ping Peng, Ai-Lin Liu, Xing-Hua Xia, Wei Chen.  (2017)  Chitosan-stabilized platinum nanoparticles as effective oxidase mimics for colorimetric detection of acid phosphatase.  Nanoscale,  9  (29): (10292-10300).  [PMID:28702672] [10.1039/C7NR03399K]

10. Jiao-Jiao Yuan, Frank G.F. Qin, Jun-Ling Tu, Bing Li.  (2017)  Preparation, Characterization, and Antioxidant Activity Evaluation of Liposomes Containing Water-Soluble Hydroxytyrosol from Olive.  MOLECULES,  22  (6): (870).  [PMID:28538693] [10.3390/molecules22060870]

11. Jiahao Xu, Dongzhe Zou, Enyu Dong, Xingyu Jiang, Shuo Xu, Yusheng Xiao, Wensheng Gong, Yini Xu, Zenan Zeng, Kefurong Deng, Yachao Li, Xianghui Xu.  (2025)  Biomedical Engineering on Smart Polymeric Nanoparticle–Hydrogel Platforms for Efficient Antibiotic Delivery against Bacterial-Infected Wounds.  ACS Biomaterials Science & Engineering,      [PMID:39977696] [10.1021/acsbiomaterials.4c02045]

12. Feng L., Yang J., Wang J., Meng S., Yu H., Han L., Zhong W..  (2024)  Groundbreaking Benzofused Hybrid Drug: Light-Responsive Reversible Absorption and Release in Hydrogel for Treating Kashin–Beck Disease.  RUSSIAN JOURNAL OF GENERAL CHEMISTRY,  94  (9): (2356-2364).  [PMID:] [10.1134/S1070363224090160]

13. Kaiyang Zhu, Ji Ma, Hafiz Muhammad Mubeen, Ting Zhang, Hongjie Lei, Wenge Zhao, Huaide Xu, Mei Li.  (2025)  Preparation, structural characterization and in vitro digestibility mechanism of walnut oil body emulsion gels based on crosslinking of edible polysaccharide and vanillin.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2025.111167]

14. Kaiyuan Zheng, Lili Wang, Xiaofan Zhang, Chengwei Hou, Aiqi Su, Shoukang Hu, Ming Yue, Xiaobiao Shan.  (2025)  The influence of functional groups on the triboelectric properties of chitosan derivatives and the electron transfer mechanism of insulators.  Nano Energy,      [PMID:] [10.1016/j.nanoen.2025.110709]

15. Jiawei Hu, Shaogang Hu, Jing Zhang, Xiangqian Xu, Jie Wu.  (2025)  Thermal hydrolysis assists calcium hypochlorite pretreatment to enhance anaerobic digestion performance of waste activated sludge.  Journal of Water Process Engineering,      [PMID:] [10.1016/j.jwpe.2025.107094]

16. Suozhu Wu, Yiqin Zhang, Xuedong Jia, Hao Wu, Jie Mao, Meijun Huo, Hongyuan Guo.  (2025)  Rapid and sensitive detection of chloramphenicol using polyaniline nanorods/reduced graphene oxide-based molecularly imprinted electrochemical sensor.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.112687]