Enpp-1-IN-14 - ≥99% , CAS No.2687222-59-7

CAS: 2687222-59-7 Cat. No.: E649281 Formule: C₁₅H₂₂ClN₅O₄S Poids moléculaire: 403.88

GRADE & PURITY ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

Enpp-1-IN-14 (Compound 015) is a potent Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) inhibitor with an IC 50 value of 32.38 nM for recombinant human ENPP-1 . Enpp-1-IN-14 has anti-tumor activity

In Vivo

Enpp-1-IN-14 (compound 015) (50 mg/kg; IP; BID, for 31 days) significantly inhibits tumor growth . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Female C57BL/6 mice (4-6 weeks; implanted subcutaneously with 2×10 5 MC38 cells) Dosage: 50 mg/kg Administration: IP; BID, for 31 days (given a single 10 Gy exposure of focal radiation to the tumor site) Result: Significantly inhibited tumor growth.

Form:Solid

IC50& Target:IC 50 : 32.38 nM (recombinant human ENPP-1)

Specifications

Spécifications et pureté

≥99%

Mécanismes biochimiques et physiologiques

Enpp-1-IN-14 (Compound 015) is a potent Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) inhibitor with an IC 50 value of 32.38 nM for recombinant human ENPP-1 . Enpp-1-IN-14 has anti-tumor activity.

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Pureté

≥99%

Noms et identifiants

• Poids moléculaire: 403.88

Propriétés chimiques et physiques

• Solubilité: DMSO : 9.62 mg/mL (23.82 mM; Need ultrasonic)