Ethamsylate - Moligand™, ≥98% , CAS No.2624-44-4

CAS: 2624-44-4 Cat. No.: E129511 Formule: C₆H₆O₅S·C₄H₁₁N Poids moléculaire: 263.31 Numéro CE: 220-090-7

QUALITÉ & PURETÉ Moligand™, ≥98%

Synonyms

Altodor|Etamsylate (JAN/INN)|Dicynene|Etamsilato (INN-Spanish)|Diidroxi-1,4-benzenesulfonato-3-di-etilammonium|Ethamsylate (USAN)|2,5-Dihydroxybenzenesulfonic acid diethylamine salt|Diethylammonium 2,5-dihydroxybenzenesulfonate

Storage

Store at 2-8°C

Shipped In

Wet ice

Vue d’ensemble

Antifibrinolytic agent. Increases capillary endothelial resistance. Promotes platelet adhesion. Inhibits platelet disaggregating and vasodilatory prostaglandin biosynthesis and function. Enhances P-selectin membrane expression. Shows angioprotective and proaggregant effects in vivo. Orally active.

Spécifications

Synonymes

Altodor | Etamsylate (JAN/INN) | Dicynene | Etamsilato (INN-Spanish) | Diidroxi-1,4-benzenesulfonato-3-di-etilammonium | Ethamsylate (USAN) | 2,5-Dihydroxybenzenesulfonic acid diethylamine salt | Diethylammonium 2,5-dihydroxybenzenesulfonate

Spécifications et pureté

Moligand™, ≥98%

Mécanismes biochimiques et physiologiques

Antifibrinolytic agent. Increases capillary endothelial resistance. Promotes platelet adhesion. Inhibits platelet disaggregating and vasodilatory prostaglandin biosynthesis and function. Enhances P-selectin membrane expression.

Conditions de stockage de stockage

Store at 2-8°C

Expédié en

Wet ice

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureté

≥98%

Noms et identifiants

Pubchem Sid

504752832

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504752832

Sourires canoniques

CCNCC.C1=CC(=C(C=C1O)S(=O)(=O)O)O

IUPAC Name

2,5-dihydroxybenzenesulfonic acid;N-ethylethanamine

InChIKey

HBGOLJKPSFNJSD-UHFFFAOYSA-N

INCHI

1S/C6H6O5S.C4H11N/c7-4-1-2-5(8)6(3-4)12(9,10)11;1-3-5-4-2/h1-3,7-8H,(H,9,10,11);5H,3-4H2,1-2H3

Isomères SMILES

CCNCC.C1=CC(=C(C=C1O)S(=O)(=O)O)O

RTECS

DB6145000

Poids moléculaire

263.31

Reaxy-Rn

4166074

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4166074&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Benzenesulfonic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Benzenesulfonic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzenesulfonic acids and derivatives
• Alternative Parents: Benzenesulfonyl compounds 1-sulfo,2-unsubstituted aromatic compounds Hydroquinones 1-hydroxy-2-unsubstituted benzenoids Sulfonyls Organosulfonic acids Dialkylamines Organopnictogen compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Not available
• Substituents: Benzenesulfonate - Arylsulfonic acid or derivatives - Benzenesulfonyl group - 1-sulfo,2-unsubstituted aromatic compound - Hydroquinone - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Sulfonyl - Organosulfonic acid - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Secondary aliphatic amine - Secondary amine - Amine - Hydrocarbon derivative - Organic oxide - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as benzenesulfonic acids and derivatives. These are organic compounds containing a sulfonic acid or a derivative thereof that is linked to a benzene ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

Discover Target: CYP2D6

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CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

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CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

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CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)

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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

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HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 Activities)

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HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)

Discover Target: HSD17B10

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EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

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LMNA Tbio Prelamin-A/C (36751 Activities)

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HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)

Discover Target: HPGD

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Cibles associées (non humaines)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

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Plasma (328 Activities)

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Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: DMSO 53 mg/mL Water 53 mg/mL Ethanol <1 mg/mL
• Sensibilité: light and moisture sensitive
• Point de fusion (°C): 130 °C
• Poids moléculaire: 263.310 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 263.083 Da
• Monoisotopic Mass: 263.083 Da
• Topological Polar Surface Area: 115.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 252.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Foire aux questions

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2624-44-4, the molecular formula is C10H17NO5S, and the molecular weight is 263.31 g/mol. InChIKey HBGOLJKPSFNJSD-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.