C-C Bond Construction

Experimental Selection Logic for C-C Bond Construction: Understanding Fragment Coupling, Carbonyl Chain Extension, Olefination, and Late-Stage Bond-Forming Pathways by Bond-Forming Task

In C-C bond construction, three questions should be considered first: what the starting substrate is, what type of carbon fragment needs to be introduced, and whether the system can tolerate organometallic reagents, transition-metal catalysis, or relatively strong basic conditions. Based on ...