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Organic Reaction Toolbox

Browse protocols, FAQs, guidelines, and technical articles tagged “Organic Reaction Toolbox”, newest first. For research use only.

22 resources · protocols, FAQs, guidelines & articles
Article

Protection Reagents

Organic synthesis constitutes a fundamental aspect of organic chemistry, enabling the preparation of both naturally occurring and artificial compounds with superior properties. A common challenge arises when multiple reactive sites or functional groups coexist within a molecule, requiring ...

Updated ·2 min read
Article

1-Hydroxycyclohexyl phenyl ketone (1-HCPK)

1-Hydroxycyclohexyl phenyl ketone, which is readily accessible on the commercial market, serves as an outstanding hydrogen acceptor in hydrogen - transfer oxidation reactions. For instance, this reagent facilitates the straightforward oxidation of primary alcohols and aldehydes to their ...

Updated ·2 min read
Article

1-Fluoropyridinium triflate

1-Fluoropyridinium triflate serves as both an electrophilic fluorinating agent and a one-electron oxidant.

Updated ·1 min read
Article

Formic Acid

Formic acid can serve as both an oxidant and a reducing agent.

Updated ·1 min read
Article

ALD and CVD: Differences between Precision and High-Throughput Thin Film Deposition

The primary distinction between Atomic Layer Deposition (ALD) and Chemical Vapor Deposition (CVD) is rooted in their deposition techniques, ability to regulate film characteristics, and appropriate applications. ALD is characterized by a step-by-step, self-terminating process that builds thin ...

Updated ·4 min read
Article

CVD and ALD Precursors

Chemical vapor deposition (CVD) is a technique that employs gaseous or vaporized materials to react within the gas phase or at the gas-solid boundary, resulting in the formation of solid coatings. Atomic layer deposition (ALD), a specialized form of CVD, enables precise deposition at the atomic ...

Updated ·4 min read
Article

N-Fluorobenzenesulfonimide (NFSI)

N-Fluorobenzenesulfonimide serves as a gentle electrophilic fluorinating agent and is also capable of acting as a potent oxidant to facilitate reductive elimination processes involving transition metals.

Updated ·8 min read
Article

Spirocyclic Building Blocks for Scaffold Assembly

Currently, chemists are becoming increasingly interested in spirocyclic building block molecules containing quaternary rings. Aladdin Scientific offers a range of spiral building block products, including various types of spiral [3.3] heptanes1 and spiral [3.4] octanes2-3. These building blocks ...

Updated ·3 min read
Article

1-Hydrosilatrane

1-Hydrosilatrane, depicted in Figure 1, serves as a highly versatile hydride reagent. It can be employed in various reduction reactions to synthesize alcohols, amines, their chiral derivatives, and esters from aldehydes and ketones.

Updated ·7 min read
Article

Burgess reagent

The Burgess reagent, (Methoxycarbonylsulfamoyl)triethylammonium hydroxide is a commercially available compound that has historically found utility as a dehydrating agent. The reagent may also be used to oxidize primary and secondary alcohols to their corresponding aldehydes and ketones in ...

Updated ·1 min read
Article

N-Bromosuccinimide (NBS)

N-Bromosuccinimide (NBS) is a brominating and oxidizing agent that is used as source for bromine in radical reactions (for example: allylic brominations) and various electrophilic additions. The NBS bromination of substrates such as alcohols and amines, followed by elimination of HBr in the ...

Updated ·19 min read
Article

Sodium Hypochlorite (NaOCl)

Sodium hypochlorite is an inexpensive, strong oxidizing agent, that is used as disinfectant and bleaching agent. It is unstable as a solid, but solutions of up to 40% are commercially available that contain NaOH and NaCl as byproducts of the preparation:

Updated ·6 min read
Article

Benzoyl Peroxide (BPO)

Benzoyl peroxide is a chemical compound with structural formula (C6H5−C(=O)O−)2, often abbreviated as (BzO)2. In terms of its structure, the molecule can be described as two benzoyl (C6H5−C(=O)−, Bz) groups connected by a peroxide (−O−O−). It is a white granular solid with a faint ...

Updated ·3 min read

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