Determine the necessary mass, volume, or concentration for preparing a solution.
FTI-2153 TFA - ≥98% , CAS No.F659224
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Storage
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items
Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
FTI-2153 TFA is a potent and highly selective inhibitor of farnesyltransferase (FTase) , with an IC 50 of 1.4 nM. FTI-2153 TFA is >3000-fold more potent at blocking H-Ras ( IC 50 , 10 nM) than Rap1A processing. Anti-cancer activity.
Appearance:Solid
In Vitro:FTI-2153, inhibits bipolar spindle formation during mitosis independently of transformation and Ras and p53 mutation status in two human lung cancer cell lines. FTI-2153 increases the percentage of prometaphase cells with ring-like DNA morphology in
Biological Activity:FTI-2153 TFA is a potent and highly selective inhibitor of farnesyltransferase (FTase) , with an IC 50 of 1.4 nM. FTI-2153 TFA is >3000-fold more potent at blocking H-Ras ( IC 50 , 10 nM) than Rap1A processing. Anti-cancer activity.
Specifications
Specifications & Purity
≥98%
Storage
Store at -20°C, Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
| Canonical Smiles | CSCC[C@@H](C(OC)=O)NC(C1=CC=C(CNCC2=CN=CN2)C=C1C3=CC=CC=C3C)=O.OC(C(F)(F)F)=O |
|---|---|
| Molecular Weight | 580.62 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Solubility | DMSO : 90 mg/mL (155.01 mM; Need ultrasonic) |
|---|
Solution Calculators
Reviews
Customer Reviews
Remind me later
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.