Gap19, CAS No.1507930-57-5

CAS: 1507930-57-5 Cat. No.: G287766 Molecular Weight: 1161.44 PubChem CID: 91691126

GRADE & PURITY ≥98%

Specifications

Product Name

Gap19, CAS No.1507930-57-5

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Selective connexin 43 (Cx43) hemichannel blocker; has no effect on gap junction coupling or Panx-1 channels. Reduces mitochondrial potassium influx in cardiomyocytes and attenuates glutamate-triggered ATP release in primary astrocytes. Modestly reduces in

Sequence

KQIEIKKFK

Action Type

INHIBITOR

CAS

1507930-57-5

Molecule Type

Small molecule

Storage and Shipping

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Oligopeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Oligopeptides
• Alternative Parents: Phenylalanine and derivatives Glutamine and derivatives Glutamic acid and derivatives Isoleucine and derivatives N-acyl-L-alpha-amino acids Alpha amino acid amides Amphetamines and derivatives Medium-chain fatty acids Amino fatty acids Branched fatty acids N-acyl amines Dicarboxylic acids and derivatives Secondary carboxylic acid amides Primary carboxylic acid amides Amino acids Carboxylic acids Carbonyl compounds Hydrocarbon derivatives Monoalkylamines Organic oxides Organopnictogen compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Alpha-oligopeptide - Phenylalanine or derivatives - Glutamine or derivatives - Glutamic acid or derivatives - Isoleucine or derivatives - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - N-acyl-l-alpha-amino acid - Alpha-amino acid amide - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Amphetamine or derivatives - Medium-chain fatty acid - Branched fatty acid - Amino fatty acid - Fatty acyl - Dicarboxylic acid or derivatives - Monocyclic benzene moiety - N-acyl-amine - Fatty amide - Benzenoid - Fatty acid - Secondary carboxylic acid amide - Primary carboxylic acid amide - Amino acid - Amino acid or derivatives - Carboxamide group - Carboxylic acid - Organic nitrogen compound - Primary aliphatic amine - Carbonyl group - Organonitrogen compound - Organooxygen compound - Primary amine - Hydrocarbon derivative - Organic oxide - Amine - Organopnictogen compound - Organic oxygen compound - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y