Gimeracil - 10mM in DMSO , Dihydropyrimidine dehydrogenase inhibitor, CAS No.103766-25-2, Dihydropyrimidine dehydrogenase inhibitor

CAS: 103766-25-2 Cat. No.: G408465 Formule: C5H4ClNO2 Poids moléculaire: 145.54 Beilstein Registry Number: 21(4)2059 Numéro CE: 870-589-4
DISPONIBLE À COMMANDE
GRADE & PURITY 10mM in DMSO
Synonyms
5-​chloro-​4-​hydroxy-2(1H)​-​pyridinone
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Allemagne (EU)
USA*
Price
Qty
1ml
G408465-1ml
—
2 En stock

101,44€

147,43€
Enregistrer 45,99 € (31.19%)
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Vue d’ensemble

Information

Gimeracil Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase, which inhibits the early step in homologous recombination for double strand breaks repair.
In vitro


In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Synonymes
5-​chloro-​4-​hydroxy-2(1H)​-​pyridinone
Spécifications et pureté
10mM in DMSO
Mécanismes biochimiques et physiologiques
Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase, which inhibits the early step in homologous recombination for double strand breaks repair.
Conditions de stockage de stockage
Store at -80°C
Expédié en
Dry ice packs + Cold packs
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Type d'action
INHIBITOR
Mécanisme d'action
Dihydropyrimidine dehydrogenase inhibitor
Propriétés du produit
ALogP-0.1
Noms et identifiants
Isomères SMILES C1=C(C(=CNC1=O)Cl)O
Poids moléculaire 145.54
Beilstein 21(4)2059
Reaxy-Rn 6135922
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6135922&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificats (CoA, COO, BSE/TSE et tableau d'analyse)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propriétés chimiques et physiques
Point de fusion (°C)274°C(dec.)(lit.)
Citations of This Product
Références
1. Hanwen Liu, Ying Liu, Ting Zhou, Penghui Zhou, Jianguo Li, Anping Deng.  (2022)  Ultrasensitive and Specific Detection of Anticancer Drug 5-Fluorouracil in Blood Samples by a Surface-Enhanced Raman Scattering (SERS)-Based Lateral Flow Immunochromatographic Assay.  MOLECULES,  27  (13): (4019).  [PMID:35807264] [10.3390/molecules27134019]
2. Ting Zhou, Guangzhao He, Changjia Hu, Kang Wu, Ying Liu, Jianguo Li, Anping Deng.  (2022)  Development of a highly sensitive and specific monoclonal antibody-based ELISA coupled with immuno-affinity extraction for the detection of anticancer drug 5-fluorouracil in blood samples.  TALANTA,      [PMID:35696979] [10.1016/j.talanta.2022.123655]
Calculateurs de solution
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