GITR/CD357 Rat mAb - Primary antibody, specific to GITR/CD357, Rat IgG2b

Cat. No.: Ab105420
AVAILABLE TO ORDER
GRADE & PURITY Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE) See COA
Application
Animal Model, Flow Cytometry, Functional Assay, Stimulation
Host species
Rat
Reactive species
Mouse
Isotype
Rat IgG2b
Clone Number
DTA-1
Conjugation
Unconjugated
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10μg
Ab105420-10μg
9
$39.90
50μg
Ab105420-50μg
4
$119.90
100μg
Ab105420-100μg
2
$147.90
1mg
Ab105420-1mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$419.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Carrier Free, Azide Free, Validated, PBS Only, ≥95%(SDS-PAGE), See COA Azide Free,Carrier Free,PBS Only,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Do not freeze Ships Wet ice,Do not freeze Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Rat anti Mouse GITR/CD357 Antibody, Monoclonal (DTA-1), could be used for Flow, in vivo GITR stimulation and so on.
Application:
Flow: Use at an assay dependent concentration.
in vivo GITR stimulation: Use at an assay dependent concentration.
Protein Function
Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Specifications

Product Name
GITR/CD357 Rat mAb - Primary antibody, specific to GITR/CD357, Rat IgG2b
Synonyms
Gitr | Activation-inducible TNFR family receptor | AITR | AITRTNF receptor superfamily activation-inducible protein | CD357 antigen | CD357 | GITR | GITR-D | GITRtumor necrosis factor receptor superfamily member 18 | Glucocorticoid-induced TNFR-related pr
Specifications & Purity
Carrier Free, Azide Free, Validated, PBS Only, ≥95%(SDS-PAGE), See COA
Host species
Rat
Specificity
GITR/CD357
Immunogen
Mouse CD25+ CD4+ T cells
Conjugation
Unconjugated
Grade
Azide Free, Carrier Free, PBS Only, Validated
Isotype
Rat IgG2b
Light Chain Type
lambda
SDS-PAGE
150 kDa
Purification Method
Protein G purified
Concentration
See COA
Storage and Shipping
Shape
Liquid
Storage
Store at 2-8°C,Do not freeze
Shipped In
Wet ice,Do not freeze
Stability And Storage
Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon receipt, it is recommended to aliquot.
Images

GITR/CD357 Rat mAb (Ab105420) - Flow Cytometry
Flow Cytometry analysis of mouse splenocytes cells labelling GITR/CD357 with GITR/CD357 Rat mAb (Ab105420) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Rat IgG Isotype Control Antibody (Biotin) (Ab180310) (left panel) and detected with SA-PE (rp156150).

GITR/CD357 Rat mAb (Ab105420) - Flow Cytometry
Flow Cytometry analysis of mouse splenocytes cells labelling GITR/CD357 (red) with GITR/CD357 Rat mAb (Ab105420) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Rat IgG Isotype Control Antibody (Biotin) (Ab180310). Black - Unlabelled control, cells without incubation with primary antibody.

Application
ApplicationDilution info
Flow Cytometry

Use at an assay dependent concentration.

in vivo GITR stimulation

Use at an assay dependent concentration.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
TNFRSF18 Tbio Tumor necrosis factor receptor superfamily member 18 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0708259Certificate of AnalysisFeb 11, 2026 Ab105420
ZJ24F0708260Certificate of AnalysisFeb 11, 2026 Ab105420
ZJ24F0708261Certificate of AnalysisFeb 11, 2026 Ab105420
Documents & Articles
Solution Calculators
Reviews

Customer Reviews

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Carrier Free grade guide → View Validated grade guide → View Azide Free grade guide → View PBS Only grade guide →

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