Guan-fu base A - ≥98% , CAS No.1394-48-5

CAS: 1394-48-5 Cat. No.: G302802 Formule: C₂₄H₃₁NO₆ Poids moléculaire: 429.51 PubChem CID: 101603171

GRADE & PURITY ≥98%

Synonyms

Acehytisine; Kwan-fu base A; (2alpha,11alpha,13R)-Hetisan-2,11,13,14-tetrol 2,13-diacetate

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Vue d’ensemble

product description：

Guanfu base A is an antiarrhythmic alkaloid isolated from Aconitum coreanum and is a potent noncompetitive CYP2D6 inhibitor, with a Ki of 1.20 μM in human liver microsomes (HLMs) and a Ki of 0.37 μM for the human recombinant form (rCYP2D6). Guanfu base A is also a potent competitive inhibitor of CYP2D in monkey (Ki of 0.38 μM) and dog (Ki of 2.4 μM) microsomes. Guanfu base A also inhibits HERG channel current.

Specifications

Synonymes

Acehytisine; Kwan-fu base A; (2alpha,11alpha,13R)-Hetisan-2,11,13,14-tetrol 2,13-diacetate

Spécifications et pureté

≥98%

Conditions de stockage de stockage

Store at 2-8°C,Protected from light

Expédié en

Wet ice

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥98%

Noms et identifiants

• Pubchem Sid: 504772770
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504772770
• Sourires canoniques: CC(=O)OC1CC2(CN3C4C2C5(C1)C3C6(C(C7C(C5C6(C4)CC7=C)O)OC(=O)C)O)C
• IUPAC Name: [(1S,3S,5S,8S,9R,11R,14R,16S,17R,18S,19S)-10-acetyloxy-9,19-dihydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.01,8.05,17.07,16.09,14.014,18]nonadecan-3-yl] acetate
• InChIKey: OGNUSOJAYIHLNS-CGMBEVFJSA-N
• INCHI: 1S/C24H31NO6/c1-10-5-22-8-14-17-21(4)6-13(30-11(2)26)7-23(17)18(22)16(28)15(10)19(31-12(3)27)24(22,29)20(23)25(14)9-21/h13-20,28-29H,1,5-9H2,2-4H3/t13-,14-,15+,16+,17+,18+,19?,20-,21+,22+,23-,24-/m0/s1
• Isomères SMILES: CC(=O)O[C@H]1C[C@@]2(CN3[C@@H]4[C@H]2[C@]5(C1)[C@H]3[C@]6(C([C@H]7[C@H]([C@@H]5[C@]6(C4)CC7=C)O)OC(=O)C)O)C
• PubChem CID: 101603171
• Poids moléculaire: 429.51

Propriétés chimiques et physiques

• Sensibilité: Moisture sensitive；Light sensitive

Foire aux questions

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1394-48-5, the molecular formula is C24H31NO6, and the molecular weight is 429.51 g/mol. InChIKey OGNUSOJAYIHLNS-CGMBEVFJSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.