H-89 - Moligand™, 10 mM in DMSO , CAS No.127243-85-0

CAS: 127243-85-0 Cat. No.: H1498370 Formule: C₂₀H₂₀BrN₃O₂S Poids moléculaire: 446.36 Numéro CE: 675-767-3

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

H-89 is a potent and selective inhibitor of cyclic AMP-dependent protein kinase ( protein kinase A ) with IC 50 of 48 nM and has weak inhibition on PKG , PKC , Casein Kinase , and others kinases.

Specifications

Spécifications et pureté

Moligand™, 10 mM in DMSO

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Noms et identifiants

• Isomères SMILES: C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNC/C=C/C3=CC=C(C=C3)Br
• CAS alternatif: 130964-39-5
• Poids moléculaire: 446.36
• Reaxy-Rn: 8160271
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8160271&ln=

Propriétés chimiques et physiques

• Point d'ébullition (°C): 639.7ºC
• Point de fusion (°C): 195-200°C

Références

1. Yong Chang, Fengli Gao, Tong Wu, Qiuzhi Pan, Lin Liu, Qijun Song.  (2023)  Electrochemical detection of protein kinases with methylene blue-functionalized Zr-based metal-organic frameworks as signal labels.  International Journal of Electrochemical Science,      [PMID:] [10.1016/j.ijoes.2023.100338]

2. Yong Chang, Xiaohua Ma, Ting Sun, Lin Liu, Yuanqiang Hao.  (2021)  Electrochemical detection of kinase by converting homogeneous analysis into heterogeneous assay through avidin-biotin interaction.  TALANTA,      [PMID:34364458] [10.1016/j.talanta.2021.122649]

3. Zhiqiang Chen, Ying Liu, Lijie Hao, Zhencai Zhu, Fang Li, Shufeng Liu.  (2018)  Reduced Graphene Oxide-Zirconium Dioxide–Thionine Nanocomposite Integrating Recognition, Amplification, and Signaling for an Electrochemical Assay of Protein Kinase Activity and Inhibitor Screening.  ACS Applied Bio Materials,      [PMID:34996206] [10.1021/acsabm.8b00451]

Foire aux questions

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 127243-85-0, the molecular formula is C20H20BrN3O2S, and the molecular weight is 446.36 g/mol.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.