Hexahydrocurcumin - Moligand™, 10 mM in DMSO , CAS No.36062-05-2

CAS: 36062-05-2 Cat. No.: H1499835 Molecular Weight: 374.43

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Hexahydrocurcumin is one of the major metabolites of curcumin and a selective, orally active COX-2 inhibitor. Hexahydrocurcumin is inactive against COX-1 . Hexahydrocurcumin has antioxidant, anticancer and anti-inflammatory activities .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Names and Identifiers

• Isomeric SMILES: COC1=C(C=CC(=C1)CCC(CC(=O)CCC2=CC(=C(C=C2)O)OC)O)O
• Molecular Weight: 374.43
• Reaxy-Rn: 2486876
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2486876&ln=

References

1. Jiaying Hao, Yunju Zhang, Kaiwei Liu, Boyu Zhang, Hao Wang, Yuning Jin, Bin Wang, Di Wang, Ying Li, Xueli Wei, Qinyuan Ma, Xiuzhen Gao.  (2025)  Structure-Guided Evolution of Curcumin Reductase for Sustainable Tetrahydrocurcumin Biosynthesis.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:41026119] [10.1021/acs.jafc.5c07455]

2. Dan Yuan, Qi Li, Qibo Zhang, Feibai Zhou, Qiangzhong Zhao, Mouming Zhao.  (2023)  Enhanced curcumin transportation across epithelial barrier by mucus-permeable soy protein nanoparticles-mediated dual transcytosis pathways.  FOOD CHEMISTRY,      [PMID:37897825] [10.1016/j.foodchem.2023.137771]