HMN-154 - Moligand™,≥98% , CAS No.173528-92-2

CAS: 173528-92-2 Cat. No.: H412301 Formule: C₂₀H₁₈N₂O₃S Poids moléculaire: 366.43

GRADE & PURITY Moligand™, ≥98%

Synonyms

4-methoxy-N-{2-[(1E)-2-(pyridin-4-yl)ethenyl]phenyl}benzene-1-sulfonamide | PK04_181116 | (E)-4-[2-[2-[[(p-Methoxyphenyl)sulfonyl]amino]phenyl]ethenyl]pyridine | C73327 | Hmn 154 | (E)-4-(2-(2-(N-(4-Methoxybenzenesulfonyl)amino)phenyl)ethenyl)pyridine | B

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

HMN-154 is a novel benzenesulfonamide anticancer compound, interacts with NF-YB and disrupts the binding of the NF-Y heterotrimer to DNA.

Specifications

Synonymes

4-methoxy-N-{2-[(1E)-2-(pyridin-4-yl)ethenyl]phenyl}benzene-1-sulfonamide | PK04_181116 | (E)-4-[2-[2-[[(p-Methoxyphenyl)sulfonyl]amino]phenyl]ethenyl]pyridine | C73327 | Hmn 154 | (E)-4-(2-(2-(N-(4-Methoxybenzenesulfonyl)amino)phenyl)ethenyl)pyridine | B

Spécifications et pureté

Moligand™,≥98%

Mécanismes biochimiques et physiologiques

HMN-154 is a novel benzenesulfonamide anticancer compound that inhibits KB and colon38 cells with IC50 of 2.6 ng/mL and 3 ng/mL, respectively.

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Pureté

≥98%

Noms et identifiants

• Sourires canoniques: COC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C=CC3=CC=NC=C3
• IUPAC Name: 4-methoxy-N-[2-[(E)-2-pyridin-4-ylethenyl]phenyl]benzenesulfonamide
• InChIKey: CIJCDFMGZYKSSC-VOTSOKGWSA-N
• INCHI: 1S/C20H18N2O3S/c1-25-18-8-10-19(11-9-18)26(23,24)22-20-5-3-2-4-17(20)7-6-16-12-14-21-15-13-16/h2-15,22H,1H3/b7-6+
• Isomères SMILES: COC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2/C=C/C3=CC=NC=C3
• Poids moléculaire: 366.43
• Reaxy-Rn: 53863389
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=53863389&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Sulfanilides

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Sulfanilides
• Intermediate Tree Nodes: Not available
• Direct Parent: Sulfanilides
• Alternative Parents: Benzenesulfonamides Benzenesulfonyl compounds Anisoles Styrenes Methoxybenzenes Phenoxy compounds Alkyl aryl ethers Pyridines and derivatives Organosulfonamides Heteroaromatic compounds Aminosulfonyl compounds Azacyclic compounds Organic oxides Hydrocarbon derivatives Organonitrogen compounds Organopnictogen compounds
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Sulfanilide - Benzenesulfonamide - Benzenesulfonyl group - Styrene - Methoxybenzene - Phenol ether - Phenoxy compound - Anisole - Alkyl aryl ether - Pyridine - Organosulfonic acid amide - Aminosulfonyl compound - Sulfonyl - Heteroaromatic compound - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Azacycle - Organoheterocyclic compound - Ether - Organic nitrogen compound - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as sulfanilides. These are organic aromatic compounds containing a sulfanilide moiety, with the general structure RS(=O)(=O)NC1=CC=CC=C1.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriétés chimiques et physiques

• Poids moléculaire: 366.400 g/mol
• XLogP3: 3.500
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 366.104 Da
• Monoisotopic Mass: 366.104 Da
• Topological Polar Surface Area: 76.700 Ų
• Heavy Atom Count: 26
• Formal Charge: 0
• Complexity: 544.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1

Foire aux questions

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 173528-92-2, the molecular formula is C20H18N2O3S, and the molecular weight is 366.43 g/mol. InChIKey CIJCDFMGZYKSSC-VOTSOKGWSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.