HS024 TFA, Antagonist of MC 1 receptor;Antagonist of MC 3 receptor;Antagonist of MC 4 receptor;Antagonist of MC 5 receptor, CAS No.212370-59-7(free base), Antagonist of MC 1 receptor;Antagonist of MC 3 receptor;Antagonist of MC 4 receptor;Antagonist of MC 5 receptor

CAS: 212370-59-7(free base) Cat. No.: H288535 Formule: C₅₈H₇₉N₁₉O₁₀S₂(free base) Poids moléculaire: 1266.50(free base)

QUALITÉ & PURETÉ Moligand™, ≥95%

Spécifications

Product Name

HS024 TFA, Antagonist of MC 1 receptor;Antagonist of MC 3 receptor;Antagonist of MC 4 receptor;Antagonist of MC 5 receptor, CAS No.212370-59-7(free base)

Synonymes

AKOS024456803 | HS 024 | N-Acetyl-L-cysteinyl-L-norleucyl-L-arginyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophylglycyl-L-cysteinamide cyclic (1->9)disulfide | HS024 | DTXSID301034918 | Long Name (Added to Synonym)

Grade

Moligand™

Spécifications et pureté

Moligand™, ≥95%

Mécanismes biochimiques et physiologiques

Highly potent melanocortin MC4receptor antagonist (Kivalues are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3and MC5receptors respectively). Increases food intake, and blocksα-MSH- and MTII-induced hypotension and bradycardia in rats, follow

Séquence

CXRHXRWGC(Modifications: Cys-1 = N-terminal Ac, X-2 = Nle, X-5 = Nal, Cys-9 = C-terminal amide, Disulfide bridge between 1 - 9)

Type d'action

ANTAGONIST

Mécanisme d'action

Antagonist of MC 1 receptor;Antagonist of MC 3 receptor;Antagonist of MC 4 receptor;Antagonist of MC 5 receptor

CAS

212370-59-7(free base)

Type de molécule

Peptide

Stockage et expédition

Conditions de stockage de stockage

Store at -20°C,Desiccated

Expédié en

Ice chest + Ice pads

Cibles associées (humaines)

MC5R Tchem Melanocortin receptor 5 (0 Activities)

Discover Target: MC5R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MC4R Tclin Melanocortin receptor 4 (0 Activities)

Discover Target: MC4R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MC3R Tchem Melanocortin receptor 3 (0 Activities)

Discover Target: MC3R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MC1R Tclin Melanocyte-stimulating hormone receptor (0 Activities)

Discover Target: MC1R

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Informations génétiques

• Alternate Names: AKOS024456803 | HS 024 | N-Acetyl-L-cysteinyl-L-norleucyl-L-arginyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophylglycyl-L-cysteinamide cyclic (1->9)disulfide | HS024 | DTXSID301034918 | Long Name (Added to Synonym)
• Reference:
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Foire aux questions

What is the purity of this product?

This product is supplied at ≥95% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 212370-59-7(free base).

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.