IMM-H007 - ≥98% , CAS No.1221412-23-2

CAS: 1221412-23-2 Cat. No.: I413115 Formule: C₂₂H₂₃N₅O₈ Poids moléculaire: 485.45 PubChem CID: 154730591

GRADE & PURITY ≥98%

Synonyms

Adenosine,N-​(3-​hydroxyphenyl)​-​,2',​3',​5'-​triacetate

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

Information

IMM-H007 IMM-H007, an adenosine derivative, is an activator of AMP-Activated Protein Kinase (AMPK) . IMM-H007 is a potential drug for treating cardiac dysfunction. IMM-H007 negatively regulates endothelium inflammation through inactivating NF-κB and JNK/AP1 signaling. IMM-H007 inhibits ABCA1 (ATP binding cassette subfamily a member 1) degradation and facilitates its cell-surface localization in macrophages, thereby promotes cholesterol efflux.

Targets

AMPK ; NF-κB ; JNK/AP1 ; ABCA1

Specifications

Synonymes

Adenosine,N-​(3-​hydroxyphenyl)​-​,2',​3',​5'-​triacetate

Spécifications et pureté

≥98%

Mécanismes biochimiques et physiologiques

IMM-H007, an adenosine derivative, is an activator of AMP-Activated Protein Kinase (AMPK). IMM-H007 is a potential drug for treating cardiac dysfunction. IMM-H007 negatively regulates endothelium inflammation through inactivating NF-κB and JNK/AP1 signali

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

ACTIVATOR

Pureté

≥98%

Noms et identifiants

• Pubchem Sid: 504773669
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504773669
• Sourires canoniques: CC(=O)OCC1CCC(O1)N2C=NC3=C(N=CN=C32)NC4=CC(=CC=C4)O
• IUPAC Name: [(2R,5R)-5-[6-(3-hydroxyanilino)purin-9-yl]oxolan-2-yl]methyl acetate
• InChIKey: XSGYPRXHHAULBZ-HUUCEWRRSA-N
• INCHI: 1S/C18H19N5O4/c1-11(24)26-8-14-5-6-15(27-14)23-10-21-16-17(19-9-20-18(16)23)22-12-3-2-4-13(25)7-12/h2-4,7,9-10,14-15,25H,5-6,8H2,1H3,(H,19,20,22)/t14-,15-/m1/s1
• PubChem CID: 154730591
• Poids moléculaire: 485.45

Propriétés chimiques et physiques

• Solubilité: Solubility (25°C) In vitro DMSO: 97 mg/mL (199.81 mM); Water: Insoluble; Ethanol: Insoluble

Foire aux questions

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1221412-23-2, the molecular formula is C22H23N5O8, and the molecular weight is 485.45 g/mol. InChIKey XSGYPRXHHAULBZ-HUUCEWRRSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.