Impentamine dihydrobromide , CAS No.149629-70-9

CAS: 149629-70-9 Cat. No.: I287603 Formule: C₈H₁₅N₃•2HBr Poids moléculaire: 315.05 PubChem CID: 53439849

Synonyms

5-(1H-Imidazol-5-yl)pentan-1-amine--hydrogen bromide (1/2) | AKOS024456820 | VUF 4702 | Impentamine dihydrobromide | DTXSID20702190 | 5-(1H-Imidazol-5-yl)pentan-1-amine dihydrobromide | 4-(5-AMINOPENTYL)IMIDAZOLE DIHYDROBROMIDE | 5-(1H-imidazol-5-yl)penta

Storage

Room temperature,Desiccated

Shipped In

Normal

Specifications

Synonymes

5-(1H-Imidazol-5-yl)pentan-1-amine--hydrogen bromide (1/2) | AKOS024456820 | VUF 4702 | Impentamine dihydrobromide | DTXSID20702190 | 5-(1H-Imidazol-5-yl)pentan-1-amine dihydrobromide | 4-(5-AMINOPENTYL)IMIDAZOLE DIHYDROBROMIDE | 5-(1H-imidazol-5-yl)penta

Mécanismes biochimiques et physiologiques

Potent and highly selective histamine H3receptor antagonist (pA2= 8.4); displays > 30000-fold selectivity over H1and H2receptors. Can act as a partial agonist in SK-N-MC cells expressing human H3receptors. Produces antinociception, possibly via a non-H1,

Conditions de stockage de stockage

Room temperature,Desiccated

Expédié en

Normal

Type d'action

INHIBITOR

Noms et identifiants

Sourires canoniques

C1=C(NC=N1)CCCCCN.Br.Br

IUPAC Name

5-(1H-imidazol-5-yl)pentan-1-amine;dihydrobromide

InChIKey

QSDXAAWBBPWGEL-UHFFFAOYSA-N

INCHI

1S/C8H15N3.2BrH/c9-5-3-1-2-4-8-6-10-7-11-8;;/h6-7H,1-5,9H2,(H,10,11);2*1H

Isomères SMILES

C1=C(NC=N1)CCCCCN.Br.Br

PubChem CID

53439849

Poids moléculaire

315.05

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Classe Organonitrogen compounds
      • Subclass Amines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Classe: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Not available
• Direct Parent: Aralkylamines
• Alternative Parents: Imidazoles Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Monoalkylamines Hydrocarbon derivatives Hydrobromides
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Aralkylamine - Heteroaromatic compound - Imidazole - Azole - Azacycle - Organoheterocyclic compound - Organopnictogen compound - Hydrocarbon derivative - Hydrobromide - Primary amine - Primary aliphatic amine - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as aralkylamines. These are alkylamines in which the alkyl group is substituted at one carbon atom by an aromatic hydrocarbyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Cibles associées (humaines)

HRH3 Tclin Histamine H3 receptor (1 Activities)

Discover Target: HRH3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HRH3 Tclin Histamine H3 receptor (10389 Activities)

Discover Target: HRH3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cibles associées (non humaines)

Hrh4 Histamine H4 receptor (388 Activities)

Discover Target: Hrh4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Solvent:water, Max Conc. mg/mL: 31.51, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 31.51, Max Conc. mM: 100
• Poids moléculaire: 315.050 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 314.977 Da
• Monoisotopic Mass: 312.979 Da
• Topological Polar Surface Area: 54.700 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 95.300
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

Foire aux questions

How should this product be stored?

Store at room temperature, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 149629-70-9, the molecular formula is C8H15N3?(HBr), and the molecular weight is 315.05 g/mol. InChIKey QSDXAAWBBPWGEL-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.