IMR-1A - ≥97% , CAS No.331862-41-0

CAS: 331862-41-0 Cat. No.: I412257 Formule: C₁₃H₁₁NO₅S₂ Poids moléculaire: 325.36

GRADE & PURITY ≥97%

Synonyms

Acetic acid,2-​[2-​methoxy-​4-​[(4-​oxo-​2-​thioxo-​5-​thiazolidinylidene)​methyl]​phenoxy]​-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

Information

IMR-1A IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.

Targets

Notch (Cell-free assay); Notch (Cell-free assay) 0.5 μM; 2.9 μM(Kd)

Specifications

Synonymes

Acetic acid,2-​[2-​methoxy-​4-​[(4-​oxo-​2-​thioxo-​5-​thiazolidinylidene)​methyl]​phenoxy]​-

Spécifications et pureté

≥97%

Mécanismes biochimiques et physiologiques

IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥97%

Propriétés du produit

• ALogP: 2.29
• hba_count: 4
• Nombre de HBD: 1
• Liaison rotative: 5

Noms et identifiants

• Pubchem Sid: 488191798
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488191798
• Sourires canoniques: COC1=C(C=CC(=C1)C=C2C(=O)NC(=S)S2)OCC(=O)O
• IUPAC Name: 2-[2-methoxy-4-[(E)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid
• InChIKey: DVBJNSKWHSGTDK-BJMVGYQFSA-N
• INCHI: 1S/C13H11NO5S2/c1-18-9-4-7(2-3-8(9)19-6-11(15)16)5-10-12(17)14-13(20)21-10/h2-5H,6H2,1H3,(H,15,16)(H,14,17,20)/b10-5+
• Poids moléculaire: 325.36
• Reaxy-Rn: 29764446
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29764446&ln=

Propriétés chimiques et physiques

• Solubilité: Solubility (25°C) In vitro DMSO: 6 mg/mL (18.44 mM); Water: Insoluble; Ethanol: Insoluble
• DMSO (mg/mL) Solubilité maximale: 6
• DMSO (mM) Solubilité maximale: 18.4411113843128
• Eau (mg/mL) Solubilité maximale: ＜1

Foire aux questions

What is the purity of this product?

This product is supplied at ≥97% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 331862-41-0, the molecular formula is C13H11NO5S2, and the molecular weight is 325.36 g/mol. InChIKey DVBJNSKWHSGTDK-BJMVGYQFSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.