KR-33493 - 10mM in DMSO , CAS No.1021497-97-1

CAS: 1021497-97-1 Cat. No.: K655575 Formule: C₂₀H₁₈BrN₃O₃S Poids moléculaire: 460.34 PubChem CID: 25009726

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

KR-33493 is a potent inhibitor of Fas-mediated cell death ( FAF1 ).

In Vivo

Body weight changes of both sexes are not related to KR-33493 in all doses. In rats administrated KR-33493 for 4 weeks, no test article-related changes in any treated groups of either sex are found in hematology, serum biochemistry, and urinalysis. In dogs administrated KR-33493 for 2 weeks, red blood cell count (RBC) value in males is significantly higher at the 1000 mg/kg/day dose than that of the control group (i.e., 6.96±0.323 vs. 6.12±0.418). However, the change of RBC is recovered after the end of the administration period. The dose-normalized AUC last is not significantly different between the groups, suggesting that KR-33493 is governed by linear kinetics . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Fas

Specifications

Spécifications et pureté

10mM in DMSO

Mécanismes biochimiques et physiologiques

KR-33493 is a potent inhibitor of Fas-mediated cell death ( FAF1 ).

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Noms et identifiants

• Isomères SMILES: C1=CC=C(C=C1)CCN2C=C(C(=N2)C(=O)O)NC(=O)CSC3=CC=C(C=C3)Br
• CAS alternatif: 1021497-97-1
• PubChem CID: 25009726
• Termes d'entrée MeSH: KM-819
• Poids moléculaire: 460.34

Foire aux questions

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1021497-97-1, the molecular formula is C20H18BrN3O3S, and the molecular weight is 460.34 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.