Lalistat 2 - ≥95% , CAS No.1234569-09-5

CAS: 1234569-09-5 Cat. No.: L288746 Formule: C13H20N4O2S Poids moléculaire: 296.39
DISPONIBLE À COMMANDE
GRADE & PURITY ≥95%
Synonyms
4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1-carboxylate | 1-Piperidinecarboxylic acid 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester, Lalistat-2
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Size
Allemagne (EU)
USA*
Price
Qty
5mg
L288746-5mg
—
5 En stock

56,32€

84,95€
Enregistrer 28,64 € (33.71%)
10mg
L288746-10mg
—
3 En stock

100,57€

150,90€
Enregistrer 50,33 € (33.35%)
25mg
L288746-25mg
—
2 En stock

219,45€

329,65€
Enregistrer 110,20 € (33.43%)
50mg
L288746-50mg
—
2 En stock

393,87€

590,84€
Enregistrer 196,98 € (33.34%)
100mg
L288746-100mg
—
1 En stock

668,07€

1 002,15€
Enregistrer 334,08 € (33.34%)
200mg
L288746-200mg
—
1 En stock

1 202,60€

1 803,94€
Enregistrer 601,34 € (33.33%)
Enter a quantity for the sizes you want to add.
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Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Vue d’ensemble

Application

Lalistat 2 has been used as a lysosomal acid lipase (LAL) inhibitor to study its effects on hypoxia-inducible factor (HIF) in mice. It has also been used as a LAL inhibitor to study LAL activity on dried blood spot cards.

Specifications

Synonymes
4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl piperidine-1-carboxylate | 1-Piperidinecarboxylic acid 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester, Lalistat-2
Spécifications et pureté
≥95%
Mécanismes biochimiques et physiologiques
Selective lysosomal acid lipase inhibitor (IC50= 152 nM). Exhibits no inhibition of human pancreatic lipase or bovine milk lipoprotein lipase (up to 10 μM).Lalistat-2 is a potent and specific competitive inhibitor of the lysosomal acid lipase (LAL/Lipa).
Conditions de stockage de stockage
Store at -20°C
Expédié en
Ice chest + Ice pads
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Pureté
≥95%
Noms et identifiants
Pubchem Sid488201389
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488201389
Sourires canoniquesC1CCN(CC1)C2=NSN=C2OC(=O)N3CCCCC3
IUPAC Name(4-piperidin-1-yl-1,2,5-thiadiazol-3-yl) piperidine-1-carboxylate
InChIKeyPNYYVHOTXOEBEV-UHFFFAOYSA-N
INCHI1S/C13H20N4O2S/c18-13(17-9-5-2-6-10-17)19-12-11(14-20-15-12)16-7-3-1-4-8-16/h1-10H2
Isomères SMILES C1CCN(CC1)C2=NSN=C2OC(=O)N3CCCCC3
Poids moléculaire 296.39
Reaxy-Rn 20694908
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20694908&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassePiperidines
SubclassPiperidinecarboxylic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentPiperidinecarboxylic acids
Alternative Parents Dialkylarylamines  Imidolactams  Thiadiazoles  Heteroaromatic compounds  Carbamate esters  Azacyclic compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Piperidinecarboxylic acid - Dialkylarylamine - Imidolactam - Azole - Thiadiazole - Carbamic acid ester - Heteroaromatic compound - Tertiary amine - Azacycle - Organic oxygen compound - Amine - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Organic oxide - Carbonyl group - Hydrocarbon derivative - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as piperidinecarboxylic acids. These are compounds containing a piperidine ring which bears a carboxylic acid group.
External Descriptors Not available
Structure 3D
Modèle de structure chimique interactif





Cibles associées (humaines)
LIPA Tchem Lysosomal acid lipase/cholesteryl ester hydrolase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
LIPA Tchem Lysosomal acid lipase/cholesteryl ester hydrolase (63 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cibles associées (non humaines)
lipO Probable esterase LipO (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lipN Probable lipase/esterase LipN (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lipI Probable lipase LipH (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lipM Probable esterase LipM (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lipR Putative acetyl-hydrolase LipR (2 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lipT Carboxylic ester hydrolase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mécanismes d'action
Certificats (CoA, COO, BSE/TSE et tableau d'analyse)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

13 results found

Lot NumberCertificate TypeDateArticle
E2619154Certificate of AnalysisMay 27, 2026 L288746
D23211127Certificate of AnalysisMar 18, 2023 L288746
D23211188Certificate of AnalysisMar 18, 2023 L288746
D23211293Certificate of AnalysisMar 18, 2023 L288746
D23211300Certificate of AnalysisMar 18, 2023 L288746
D23211306Certificate of AnalysisMar 18, 2023 L288746
D23211307Certificate of AnalysisMar 18, 2023 L288746
D23211309Certificate of AnalysisMar 18, 2023 L288746
D23211329Certificate of AnalysisMar 18, 2023 L288746
D23211343Certificate of AnalysisMar 18, 2023 L288746
D23211354Certificate of AnalysisMar 18, 2023 L288746
D23211370Certificate of AnalysisMar 18, 2023 L288746
D23211378Certificate of AnalysisMar 18, 2023 L288746

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Propriétés chimiques et physiques
SolubilitéSolvent:DMSO, Max Conc. mg/mL: 29.64, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 29.64, Max Conc. mM: 100
Poids moléculaire296.390 g/mol
XLogP32.600
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass296.131 Da
Monoisotopic Mass296.131 Da
Topological Polar Surface Area86.800 Ų
Heavy Atom Count20
Formal Charge0
Complexity332.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculateurs de solution
Avis

Avis des clients

Foire aux questions

What is the purity of this product?
This product is supplied at ≥95% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 1234569-09-5, the molecular formula is C??H??N?O?S, and the molecular weight is 296.39 g/mol. InChIKey PNYYVHOTXOEBEV-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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