Découvrez des composés axés sur les voies métaboliques destinés à la recherche en épigénétique, notamment des outils liés à la régulation de la chromatine et au contrôle transcriptionnel. Utilisez cette page pour comparer les molécules employées dans les processus de validation des cibles, d'étude des mécanismes et de modulation de l'état cellulaire.
Épigénétique
Produits
- OAC1CAS: 300586-90-7 Formule: C14H11N3O Poids moléculaire: 237.2610mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: O423084Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- N-(1H-pyrrolo[2,3-c]pyridin-5-yl)benzamide
- SMILES
- C1=CC=C(C=C1)C(=O)NC2=NC=C3C(=C2)C=CN3
- InChIKey
- HWJRIFZDXJKJJN-UHFFFAOYSA-N
- InChI
- 1S/C14H11N3O/c18-14(10-4-2-1-3-5-10)17-13-8-11-6-7-15-12(11)9-16-13/h1-9,15H,(H,16,17,18)
- Synonymes
- OAC-1;Oct4-activating Compound 1;N-1H-Pyrrolo[2,3-c]pyridin-5-ylbenzamide
- OF 1, bromodomain and PHD finger containing 1;bromodomain and PHD finger containing 3Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: O426929Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 4-bromo-N-(6-methoxy-1,3-dimethyl-2-oxobenzimidazol-5-yl)-2-methylbenzenesulfonamide
- SMILES
- CC1=C(C=CC(=C1)Br)S(=O)(=O)NC2=CC3=C(C=C2OC)N(C(=O)N3C)C
- InChIKey
- YUNQZQREIHWDQT-UHFFFAOYSA-N
- InChI
- 1S/C17H18BrN3O4S/c1-10-7-11(18)5-6-16(10)26(23,24)19-12-8-13-14(9-15(12)25-4)21(3)17(22)20(13)2/h5-9,19H,1-4H3
- Synonymes
- OF-1|919973-83-4|SGC OF-1|OF 1|4-bromo-N-(6-methoxy-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-2-methyl...
- OG-L002, Inhibitor of lysine demethylase 1ACAS: 1357302-64-7 Formule: C15H15NO Poids moléculaire: 225.29Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: O421358Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 3-[4-[(1R,2S)-2-aminocyclopropyl]phenyl]phenol
- SMILES
- C1C(C1N)C2=CC=C(C=C2)C3=CC(=CC=C3)O
- InChIKey
- DSOJSZXQRJGBCW-CABCVRRESA-N
- InChI
- 1S/C15H15NO/c16-15-9-14(15)11-6-4-10(5-7-11)12-2-1-3-13(17)8-12/h1-8,14-15,17H,9,16H2/t14-,15+/m1/s1
- Synonymes
- 4'-((1R,2S)-2-aminocyclopropyl)biphenyl-3-ol;3-[4-[(1R,2S)-2-aminocyclopropyl]phenyl]phenol;4′-((1R,2S)-2-Aminocyclop...
- OICR 9429, Inhibitor of WD repeat domain 5Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: O422203Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- N-[2-(4-methylpiperazin-1-yl)-5-[3-(morpholin-4-ylmethyl)phenyl]phenyl]-6-oxo-4-(trifluoromethyl)-1H-pyridine-3-carboxamide
- SMILES
- CN1CCN(CC1)C2=C(C=C(C=C2)C3=CC=CC(=C3)CN4CCOCC4)NC(=O)C5=CNC(=O)C=C5C(F)(F)F
- InChIKey
- DJOVLOYCGXNVPI-UHFFFAOYSA-N
- InChI
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- Synonymes
- N-[2-(4-Methylpiperazin-1-yl)-5-[3-(morpholin-4-ylmethyl)phenyl]phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine...
- ON-123300, Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 6;Inhibitor of NUAK family kinase 1CAS: 1357470-29-1 Formule: C24H27N7O Poids moléculaire: 429.5Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: O421359Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 8-cyclopentyl-2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile
- SMILES
- CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C4C=C(C(=O)N(C4=N3)C5CCCC5)C#N
- InChIKey
- VADOZMZXXRBXNY-UHFFFAOYSA-N
- InChI
- show more
- Synonymes
- ON123300|1357470-29-1|ON-123300|narazaciclib|8-cyclopentyl-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-7-oxo-7,8-dihy...
- OTX015, Bromodomain and extra-terminal motif (BET) inhibitorCAS: 202590-98-5 Formule: C25H22ClN5O2S Poids moléculaire: 491.99Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: O422463Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- show more
- SMILES
- CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)O)C5=CC=C(C=C5)Cl)C
- InChIKey
- GNMUEVRJHCWKTO-FQEVSTJZSA-N
- InChI
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- Synonymes
- 2-((6S)-4-(4-CHLOROPHENYL)-2,3,9-TRIMETHYL-6H-THIENO(3,2- F)(1,2,4)TRIAZOLO(4,3-A)(1,4)DIAZEPIN-6-YL)- N-(4-HYDROXYPH...
- OSS_128167CAS: 887686-02-4 Formule: C19H14N2O6 Poids moléculaire: 366.32● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: O414086Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 5-[[3-(furan-2-carbonylamino)benzoyl]amino]-2-hydroxybenzoic acid
- SMILES
- C1=CC(=CC(=C1)NC(=O)C2=CC=CO2)C(=O)NC3=CC(=C(C=C3)O)C(=O)O
- InChIKey
- HTJWLEGCECXGSQ-UHFFFAOYSA-N
- InChI
- 1S/C19H14N2O6/c22-15-7-6-13(10-14(15)19(25)26)20-17(23)11-3-1-4-12(9-11)21-18(24)16-5-2-8-27-16/h1-10,22H,(H,20,23)(H,21,24)(H,25,26)
- Synonymes
- SIRT6-IN-1
- OSS_128167CAS: 887686-02-4 Formule: C19H14N2O6 Poids moléculaire: 366.3210mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: O426691Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 5-[[3-(furan-2-carbonylamino)benzoyl]amino]-2-hydroxybenzoic acid
- SMILES
- C1=CC(=CC(=C1)NC(=O)C2=CC=CO2)C(=O)NC3=CC(=C(C=C3)O)C(=O)O
- InChIKey
- HTJWLEGCECXGSQ-UHFFFAOYSA-N
- InChI
- 1S/C19H14N2O6/c22-15-7-6-13(10-14(15)19(25)26)20-17(23)11-3-1-4-12(9-11)21-18(24)16-5-2-8-27-16/h1-10,22H,(H,20,23)(H,21,24)(H,25,26)
- Synonymes
- SIRT6-IN-1
- Oclacitinib maleate10mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: O422024Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- (Z)-but-2-enedioic acid;N-methyl-1-[4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl]methanesulfonamide
- SMILES
- CNS(=O)(=O)CC1CCC(CC1)N(C)C2=NC=NC3=C2C=CN3.C(=CC(=O)O)C(=O)O
- InChIKey
- VQIGDTLRBSNOBV-BTJKTKAUSA-N
- InChI
- show more
- Synonymes
- Oclacitinib (maleate) | BS-44681 | D10142 | N-Methyl[trans-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexyl]...
- Oclacitinib maleateCAS: 1640292-55-2 Formule: C19H27N5O6S Poids moléculaire: 453.51● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: O413939Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- (Z)-but-2-enedioic acid;N-methyl-1-[4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl]methanesulfonamide
- SMILES
- CNS(=O)(=O)CC1CCC(CC1)N(C)C2=NC=NC3=C2C=CN3.C(=CC(=O)O)C(=O)O
- InChIKey
- VQIGDTLRBSNOBV-BTJKTKAUSA-N
- InChI
- show more
- Synonymes
- Oclacitinib (maleate) | BS-44681 | D10142 | N-Methyl[trans-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexyl]...
- Onametostat (JNJ-64619178), Inhibitor of protein arginine methyltransferase 5CAS: 2086772-26-9 Formule: C22H23BrN6O2 Poids moléculaire: 483.36Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%◐ .Sur commande · 8–12 semaines Article #: O414085Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- (1S,2R,3S,5R)-3-[2-(2-amino-3-bromoquinolin-7-yl)ethyl]-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-diol
- SMILES
- C1C(C(C(C1N2C=CC3=C(N=CN=C32)N)O)O)CCC4=CC5=NC(=C(C=C5C=C4)Br)N
- InChIKey
- DBSMLQTUDJVICQ-CJODITQLSA-N
- InChI
- show more
- Synonymes
- (1~{S},2~{R},3~{S},5~{R})-3-[2-(2-azanyl-3-bromanyl-quinolin-7-yl)ethyl]-5-(4-azanylpyrrolo[2,3-d]pyrimidin-7-yl)cycl...
- PF 06409577CAS: 1467057-23-3 Numéro CE: 110-458-4 PubChem CID: 71748255 Formule: C19H16ClNO3 Poids moléculaire: 341.7910mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: P421704Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 6-chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid
- SMILES
- C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=C3)C(=CN4)C(=O)O)Cl)O
- InChIKey
- FHQXLWCFSUSXBF-UHFFFAOYSA-N
- InChI
- 1S/C19H16ClNO3/c20-16-9-17-14(15(10-21-17)18(22)23)8-13(16)11-2-4-12(5-3-11)19(24)6-1-7-19/h2-5,8-10,21,24H,1,6-7H2,(H,22,23)
- Synonymes
- AKOS030211017 | CCG-267937 | PF06409577; PF 06409577; PF-6409577; PF6409577; PF 6409577 | NCGC00096915-01 | 6-chloro-...
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Foire aux questions
What should I consider when selecting an Epigenetics product?
Define the transformation first, then narrow the Epigenetics listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
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Epigenetics is organised into AMPK, Aurora Kinase, DNA Methyltransferase, Epigenetic Reader Domain and Glycosyltransferase, and 17 further subcategories. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
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Review the lot-specific Certificate of Analysis for the Epigenetics product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
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