Épigénétique

Découvrez des composés axés sur les voies métaboliques destinés à la recherche en épigénétique, notamment des outils liés à la régulation de la chromatine et au contrôle transcriptionnel. Utilisez cette page pour comparer les molécules employées dans les processus de validation des cibles, d'étude des mécanismes et de modulation de l'état cellulaire.

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  1. N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine
    CAS: 1453071-47-0 Formule: C15H27NO4 Poids moléculaire: 285.38
    ◐ .Sur commande · 8–12 semaines Article #: N159360
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    Nom IUPAC
    3-[9-cyclopropylnonanoyl(hydroxy)amino]propanoic acid
    SMILES
    C1CC1CCCCCCCCC(=O)N(CCC(=O)O)O
    InChIKey
    NEHSERYKENINRH-UHFFFAOYSA-N
    InChI
    1S/C15H27NO4/c17-14(16(20)12-11-15(18)19)8-6-4-2-1-3-5-7-13-9-10-13/h13,20H,1-12H2,(H,18,19)
    Synonymes
    AKOS025142046 | SCHEMBL20493040 | beta-Alanine, N-(9-cyclopropyl-1-oxononyl)-N-hydroxy- | MFCD28166486 | 1453071-47-0...
  2. Hypericin
    CAS: 548-04-9 Numéro CE: 208-941-0 Formule: C30H16O8 Poids moléculaire: 504.44
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: H110188
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    Nom IUPAC
    9,11,13,16,18,20-hexahydroxy-5,24-dimethyloctacyclo[13.11.1.12,10.03,8.04,25.019,27.021,26.014,28]octacosa-1(26),2,4(25),5,8,10,12,14(28),15(27),16,18show more
    SMILES
    CC1=CC(=O)C2=C(C3=C(C=C(C4=C3C5=C2C1=C6C(=CC(=O)C7=C(C8=C(C=C(C4=C8C5=C67)O)O)O)C)O)O)O
    InChIKey
    YDOIFHVUBCIUHF-UHFFFAOYSA-N
    InChI
    1S/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)25(17)27(23)28/h3-6,33-3show more
    Synonymes
    CCG-36081 | 1:6:8:10:11:13-hexahydroxy-3:4-dimethyl-meso-naphthodianthrene-7:14-dione | 4,5,7,4',5',7'-Hexahydroxy-2,...
  3. PJ34 HCl
    CAS: 344458-15-7 Formule: C17H17N3O2·HCl Poids moléculaire: 331.8
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: P129886
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    Nom IUPAC
    2-(dimethylamino)-N-(6-oxo-5H-phenanthridin-2-yl)acetamide;hydrochloride
    SMILES
    CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32.Cl
    InChIKey
    RURAZZMDMNRXMI-UHFFFAOYSA-N
    InChI
    1S/C17H17N3O2.ClH/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15;/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22);1H
    Synonymes
    A874967 | AS-72775 | HY-13688 | n-(6-oxo-5,6-dihydro-phenanthridin-2-yl)-n,n-dimethylacetamide hydrochloride | AKOS00...
  4. I-BET 151 dihydrochloride
    CAS: 1883545-47-8 PubChem CID: 121513850 Formule: C23H21N5O3•2HCl Poids moléculaire: 488.37
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: I287715
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    Nom IUPAC
    7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(1R)-1-pyridin-2-ylethyl]-3H-imidazo[4,5-c]quinolin-2-one;dihydrochloride
    SMILES
    CC1=C(C(=NO1)C)C2=C(C=C3C(=C2)N=CC4=C3N(C(=O)N4)C(C)C5=CC=CC=N5)OC.Cl.Cl
    InChIKey
    UFLKDZBLUNJNJS-FFXKMJQXSA-N
    InChI
    1S/C23H21N5O3.2ClH/c1-12-21(14(3)31-27-12)16-9-18-15(10-20(16)30-4)22-19(11-25-18)26-23(29)28(22)13(2)17-7-5-6-8-24-17;;/h5-11,13H,1-4H3,(H,26,29);2*1show more
    Synonymes
    I-BET151 dihydrochloride | GSK1210151A dihydrochloride | 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R...
  5. I-BET151, Inhibitor of bromodomain containing 2;Inhibitor of bromodomain containing 3;Inhibitor of bromodomain containing 4
    CAS: 1300031-49-5 Numéro CE: 802-803-9 Formule: C23H21N5O3 Poids moléculaire: 415.44
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: I124882
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    Nom IUPAC
    7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(1R)-1-pyridin-2-ylethyl]-3H-imidazo[4,5-c]quinolin-2-one
    SMILES
    CC1=C(C(=NO1)C)C2=C(C=C3C(=C2)N=CC4=C3N(C(=O)N4)C(C)C5=CC=CC=N5)OC
    InChIKey
    VUVUVNZRUGEAHB-CYBMUJFWSA-N
    InChI
    1S/C23H21N5O3/c1-12-21(14(3)31-27-12)16-9-18-15(10-20(16)30-4)22-19(11-25-18)26-23(29)28(22)13(2)17-7-5-6-8-24-17/h5-11,13H,1-4H3,(H,26,29)/t13-/m1/s1
    Synonymes
    BDBM50380682 | GTPL7518 | 1GH | DTXSID10680599 | 2H-Imidazo[4,5-c]quinolin-2-one, 7-(3,5-dimethyl-4-isoxazolyl)-1,3-d...
  6. I-BRD9, Inhibitor of bromodomain containing 9
    CAS: 1714146-59-4 Formule: C22H22F3N3O3S2 Poids moléculaire: 497.55
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: I287753
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    Nom IUPAC
    N'-(1,1-dioxothian-4-yl)-5-ethyl-4-oxo-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide
    SMILES
    CCN1C=C(C2=C(C1=O)C=C(S2)C(=NC3CCS(=O)(=O)CC3)N)C4=CC(=CC=C4)C(F)(F)F
    InChIKey
    WRUWGLUCNBMGPS-UHFFFAOYSA-N
    InChI
    1S/C22H22F3N3O3S2/c1-2-28-12-17(13-4-3-5-14(10-13)22(23,24)25)19-16(21(28)29)11-18(32-19)20(26)27-15-6-8-33(30,31)9-7-15/h3-5,10-12,15H,2,6-9H2,1H3,(Hshow more
    Synonymes
    5-Ethyl-4,5-dihydro-4-oxo-N-(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyri...
  7. I-CBP 112, Inhibitor of CREB binding protein;Inhibitor of E1A binding protein p300
    CAS: 1640282-31-0 Formule: C27H36N2O5 Poids moléculaire: 468.59
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: I288434
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    Nom IUPAC
    1-[7-(3,4-dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]propan-1-one
    SMILES
    CCC(=O)N1CCOC2=C(C1)C=C(C=C2OCC3CCCN(C3)C)C4=CC(=C(C=C4)OC)OC
    InChIKey
    YKNAKDFZAWQEEO-IBGZPJMESA-N
    InChI
    1S/C27H36N2O5/c1-5-26(30)29-11-12-33-27-22(17-29)13-21(20-8-9-23(31-3)24(14-20)32-4)15-25(27)34-18-19-7-6-10-28(2)16-19/h8-9,13-15,19H,5-7,10-12,16-18show more
    Synonymes
    1-[7-(3,4-Dimethoxyphenyl)-2,3-dihydro-9-[[(3S)-1-methyl-3-piperidinyl]methoxy]-1,4-benzoxazepin-4(5H)-yl]-1-propanon...
  8. Hypocrellin A
    CAS: 77029-83-5 Formule: C30H26O10 Poids moléculaire: 546.52
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: H275027
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    Nom IUPAC
    12-acetyl-9,13,17-trihydroxy-5,10,16,21-tetramethoxy-13-methylhexacyclo[13.8.0.02,11.03,8.04,22.018,23]tricosa-1(15),2(11),3(8),4(22),5,9,16,18(23),20show more
    SMILES
    CC(=O)C1C2=C3C4=C(CC1(C)O)C(=C(C5=C4C(=C6C3=C(C(=O)C=C6OC)C(=C2OC)O)C(=CC5=O)OC)O)OC
    InChIKey
    VANSZAOQCMTTPB-UHFFFAOYSA-N
    InChI
    1S/C30H26O10/c1-10(31)25-24-22-16-11(9-30(25,2)36)28(39-5)26(34)17-12(32)7-14(37-3)19(21(16)17)20-15(38-4)8-13(33)18(23(20)22)27(35)29(24)40-6/h7-8,25show more
    Synonymes
    AKOS040758769 | FT-0777753 | acetyl-trihydroxy-tetramethoxy-methyl-[?]dione | 1-Acetyl-2,6,11-trihydroxy-4,8,9,13-tet...
  9. Adriamycin, Inhibitor of DNA topoisomerase II alpha
    CAS: 23214-92-8 Numéro CE: 245-495-6 PubChem CID: 31703 Formule: C27H29NO11 Poids moléculaire: 543.5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: A183027
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    Nom IUPAC
    (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
    SMILES
    CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)O
    InChIKey
    AOJJSUZBOXZQNB-TZSSRYMLSA-N
    InChI
    1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,1show more
    Synonymes
    Adriablastin | hydroxydaunomycin | Hydroxyldaunorubicin | LMPK13050001 | NCI-C01514 | Doxorubicine | NSC-759155 | D03...
  10. Iniparib (BSI-201), Reactive nitro radical
    CAS: 160003-66-7 Numéro CE: 685-396-9 Formule: C7H5IN2O3 Poids moléculaire: 292.03
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: B125751
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    Nom IUPAC
    4-iodo-3-nitrobenzamide
    SMILES
    C1=CC(=C(C=C1C(=O)N)[N+](=O)[O-])I
    InChIKey
    MDOJTZQKHMAPBK-UHFFFAOYSA-N
    InChI
    1S/C7H5IN2O3/c8-5-2-1-4(7(9)11)3-6(5)10(12)13/h1-3H,(H2,9,11)
    Synonymes
    DTXSID30166784 | Iniparib (BSI-201) | s1087 | J-515558 | SMR004701226 | 4-iodo-5-nitro-benzamide | IND-71677 | Inipar...
  11. Inhibitor 6e (PRMT1 inhibitor 6e)
    CAS: 1025948-98-4 Formule: C20H7Br6NO5 Poids moléculaire: 820.7
    ◐ .Sur commande · 8–12 semaines Article #: I275552
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    Nom IUPAC
    4-amino-3,5-dibromo-2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxoxanthen-9-yl)benzoic acid
    SMILES
    C1=C2C(=C3C=C(C(=O)C(=C3OC2=C(C(=C1Br)O)Br)Br)Br)C4=C(C(=C(C=C4C(=O)O)Br)N)Br
    InChIKey
    PSILLVDSFALROT-UHFFFAOYSA-N
    InChI
    1S/C20H7Br6NO5/c21-7-3-6(20(30)31)11(12(24)15(7)27)10-4-1-8(22)16(28)13(25)18(4)32-19-5(10)2-9(23)17(29)14(19)26/h1-3,28H,27H2,(H,30,31)
    Synonymes
    4-Amino-3,5-dibromo-2-(2,4,5,7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoicacid
  12. Pinometostat (EPZ5676), Inhibitor of DOT1 like histone lysine methyltransferase
    CAS: 1380288-87-8 Formule: C30H42N8O3 Poids moléculaire: 562.71
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: E125307
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    Nom IUPAC
    (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-[[[3-[2-(6-tert-butyl-1H-benzimidazol-2-yl)ethyl]cyclobutyl]-propan-2-ylamino]methyl]oxolane-3,4-diol
    SMILES
    CC(C)N(CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O)C4CC(C4)CCC5=NC6=C(N5)C=C(C=C6)C(C)(C)C
    InChIKey
    LXFOLMYKSYSZQS-XKHGBIBOSA-N
    InChI
    1S/C30H42N8O3/c1-16(2)37(13-22-25(39)26(40)29(41-22)38-15-34-24-27(31)32-14-33-28(24)38)19-10-17(11-19)6-9-23-35-20-8-7-18(30(3,4)5)12-21(20)36-23/h7-show more
    Synonymes
    (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(((3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropy...
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Foire aux questions

What should I consider when selecting an Epigenetics product?
Define the transformation first, then narrow the Epigenetics listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which Epigenetics subcategory should I start with?
Epigenetics is organised into AMPK, Aurora Kinase, DNA Methyltransferase, Epigenetic Reader Domain and Glycosyltransferase, and 17 further subcategories. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering Epigenetics?
Review the lot-specific Certificate of Analysis for the Epigenetics product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Epigenetics by structure or CAS number?
Yes. Within Epigenetics you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].

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