LUF5771 - ≥98% , CAS No.1141802-49-4

CAS: 1141802-49-4 Cat. No.: L650188 Formule: C₂₄H₂₃NO₂ Poids moléculaire: 357.4 PubChem CID: 44572264

QUALITÉ & PURETÉ ≥98%

Synonyms

5-Phenyl-(1,1'-biphenyl)-3-yl N-cyclopentylcarbamate|(1,1':3',1''-Terphenyl)-5'-yl N-cyclopentylcarbamate|LUF5771|LUF-5771|Cyclopentyl-carbamic acid [1,1'',3'',1'''']terphenyl-5''-yl ester|[1,1':3',1''-Terphenyl]-5'-yl cyclopentylcarbamate|Carbamic acid, N-cyclopentyl-, (1,1':3',1''-terphenyl)-5'-yl ester

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

LUF5771 is a potent allosteric recombinant luteinizing hormone ( recLH ) and Org 43553 inhibitor. LUF5771 is able to partially activate the LH receptor with low efficacy

In Vitro

LUF5771 (1 µM or 10 µM) allosteric inhibition is concentration-dependent. LUF5771 significantly increases radioligand dissociation. LUF5771 probably binds to the seven transmembrane domain like Org 43553 does. LUF5771 (10 µM) alone is able to partially activate the LH receptor by 31±4%. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:recLH and Org 43553

Spécifications

Synonymes

5-Phenyl-(1,1'-biphenyl)-3-yl N-cyclopentylcarbamate | (1,1':3',1''-Terphenyl)-5'-yl N-cyclopentylcarbamate | LUF5771 | LUF-5771 | Cyclopentyl-carbamic acid [1,1'',3'',1'''']terphenyl-5''-yl ester | [1,1':3',1''-Terphenyl]-5'-yl cyclopentylcarbamate | Carbamic acid, N-cyclopentyl-, (1,1':3',1''-terphenyl)-5'-yl ester

Spécifications et pureté

≥98%

Mécanismes biochimiques et physiologiques

LUF5771 is a potent allosteric recombinant luteinizing hormone ( recLH ) and Org 43553 inhibitor. LUF5771 is able to partially activate the LH receptor with low efficacy.

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥98%

Noms et identifiants

Sourires canoniques

C1CCC(C1)NC(=O)OC2=CC(=CC(=C2)C3=CC=CC=C3)C4=CC=CC=C4

IUPAC Name

(3,5-diphenylphenyl) N-cyclopentylcarbamate

InChIKey

YNYOWRRXJIPCGX-UHFFFAOYSA-N

INCHI

1S/C24H23NO2/c26-24(25-22-13-7-8-14-22)27-23-16-20(18-9-3-1-4-10-18)15-21(17-23)19-11-5-2-6-12-19/h1-6,9-12,15-17,22H,7-8,13-14H2,(H,25,26)

Isomères SMILES

C1CCC(C1)NC(=O)OC2=CC(=CC(=C2)C3=CC=CC=C3)C4=CC=CC=C4

CAS alternatif

1141802-49-4

PubChem CID

44572264

Termes d'entrée MeSH

cPrCA-terphenyl ester;cyclopentylcarbamic acid (1,1',2',1'')terphenyl-5'-yl ester;LUF 5771;LUF-5771;LUF5771

Poids moléculaire

357.4

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Terphenyls

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Terphenyls
• Intermediate Tree Nodes: Not available
• Direct Parent: M-terphenyls
• Alternative Parents: Biphenyls and derivatives Phenoxy compounds Carbamate esters Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Meta-terphenyl - Biphenyl - Phenoxy compound - Carbamic acid ester - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as m-terphenyls. These are terphenyls with a structure containing the 1,3-diphenylbenzene skeleton.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Cibles associées (humaines)

LHCGR Tclin Luteinizing hormone/Choriogonadotropin receptor (373 Activities)

Discover Target: LHCGR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: DMSO : 100 mg/mL (279.77 mM; Need ultrasonic)
• Poids moléculaire: 357.400 g/mol
• XLogP3: 6.000
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 357.173 Da
• Monoisotopic Mass: 357.173 Da
• Topological Polar Surface Area: 38.300 Ų
• Heavy Atom Count: 27
• Formal Charge: 0
• Complexity: 435.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Foire aux questions

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1141802-49-4, the molecular formula is C24H23NO2, and the molecular weight is 357.4 g/mol. InChIKey YNYOWRRXJIPCGX-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.