LUF5771 is a potent allosteric recombinant luteinizing hormone ( recLH ) and Org 43553 inhibitor. LUF5771 is able to partially activate the LH receptor with low efficacy
In Vitro
LUF5771 (1 µM or 10 µM) allosteric inhibition is concentration-dependent. LUF5771 significantly increases radioligand dissociation. LUF5771 probably binds to the seven transmembrane domain like Org 43553 does. LUF5771 (10 µM) alone is able to partially activate the LH receptor by 31±4%. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:recLH and Org 43553
Spécifications
Spécifications et pureté
10mM in DMSO
Mécanismes biochimiques et physiologiques
LUF5771 is a potent allosteric recombinant luteinizing hormone ( recLH ) and Org 43553 inhibitor. LUF5771 is able to partially activate the LH receptor with low efficacy.
Conditions de stockage de stockage
Store at -80°C
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Dry ice packs + Cold packs
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Certificats (CoA, COO, BSE/TSE et tableau d'analyse)
C of A & Other Certificates(BSE/TSE, COO):
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How should this product be stored?
Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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