Name: Luteolin - Moligand™, 10mM in DMSO , Agonist of TAS2R14;Agonist of TAS2R39, CAS No.491-70-3, Agonist of TAS2R14;Agonist of TAS2R39
SKU: L409168
Availability: InStock

Luteolin - Moligand™, 10mM in DMSO , Agonist of TAS2R14;Agonist of TAS2R39, CAS No.491-70-3, Agonist of TAS2R14;Agonist of TAS2R39

CAS: 491-70-3 Cat. No.: L409168 Formule: C₁₅H₁₀O₆ Poids moléculaire: 286.24 Beilstein Registry Number: 292084 Numéro CE: 207-741-0

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Luteolin - Moligand™, 10mM in DMSO CAS No(491-70-3) by Aladdin Scientific

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DISPONIBLE À COMMANDE

GRADE & PURITY Moligand™ ? 10mM in DMSO

Synonyms

Luteoline, Luteolol, Digitoflavone | 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble Specifications Noms et identifiants Documentation Advanced Data Cibles associées (humaines) Certificats (CoA, COO, BSE/TSE et tableau d'analyse) Propriétés chimiques et physiques FAQ et articles Citations of This Product Calculateurs de solution Avis

🧪

Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 223 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Vue d’ensemble

Information

Luteolin (Luteoline, Luteolol, Digitoflavone) is a flavonoid found in Terminalia chebula, which is a non-selective phisphodiesterase PDE inhibitor for PDE1-5 with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM, respectively. Phase 2.
In vitro

Luteolin is a flavonoid found in Terminalia chebula, which is a non-selective phisphodiesterase PDE inhibitor for PDE1-5 with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM, respectively. Luteolin inhibits LPS-stimulated TNF-alpha production with an IC50 of less than 1 μM. Luteolin inhibites LPS-induced phosphorylation of Akt as well as IkappaBalpha.

In vivo

LD50: Mice >2500mg/kg (i.g.)
Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥97%

Specifications

Synonymes

Luteoline, Luteolol, Digitoflavone | 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-

Spécifications et pureté

Moligand™, 10mM in DMSO

Mécanismes biochimiques et physiologiques

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Type d'action

AGONIST

Mécanisme d'action

Agonist of TAS2R14;Agonist of TAS2R39

Noms et identifiants

Isomères SMILES

C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O

WGK Allemagne

RTECS

LK9275210

Poids moléculaire

286.24

Beilstein

292084

Reaxy-Rn

292084

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=292084&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Cibles associées (humaines)

CYP1A2 Tchem Cytochrome P450 1A2 (1 Activities)

Discover Target: CYP1A2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP1B1 Tchem Cytochrome P450 1B1 (3 Activities)

Discover Target: CYP1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DPP4 Tclin Dipeptidyl peptidase 4 (1 Activities)

Discover Target: DPP4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TTR Tclin Transthyretin (1 Activities)

Discover Target: TTR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MMP12 Tchem Macrophage metalloelastase (1 Activities)

Discover Target: MMP12

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CA4 Tclin Carbonic anhydrase 4 (1 Activities)

Discover Target: CA4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CA12 Tclin Carbonic anhydrase 12 (1 Activities)

Discover Target: CA12

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CA7 Tclin Carbonic anhydrase 7 (1 Activities)

Discover Target: CA7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP1A1 Tchem Cytochrome P450 1A1 (1 Activities)

Discover Target: CYP1A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

XDH Tclin Xanthine dehydrogenase/oxidase (1 Activities)

Discover Target: XDH

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AKR1B1 Tclin Aldose reductase (1 Activities)

Discover Target: AKR1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NOX4 Tchem NADPH oxidase 4 (1 Activities)

Discover Target: NOX4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Certificats (CoA, COO, BSE/TSE et tableau d'analyse)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number	Certificate Type	Date	Article
I2624544	Certificate of Analysis	Oct 10, 2026	L409168
L2201020	Certificate of Analysis	Aug 11, 2026	L409168

Propriétés chimiques et physiques

Solubilité	Solubility (25°C) In vitro DMSO: 38 mg/mL (102.73 mM); Water: 10 mg/mL (27.03 mM); Ethanol: 2 mg/mL (5.4 mM);
Point de fusion (°C)	330°C

FAQ et articles

Molecular Basis of Glycosylation Modification and Functional Release in Natural Products

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Natural products glycosylation modification glycosyltransferases glycosidases precursor activation functional release deglycosylation structure-activity relationship

Extraction Methods and Process Selection for Flavonoid Compounds

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

flavonoid compounds extraction methods solvent extraction ultrasound-assisted extraction microwave-assisted extraction enzyme-assisted extraction supercritical fluid extraction process optimization

Mechanisms by Which Flavonoid Natural Products Regulate the Oxidative Stress-Inflammation Axis

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Inflammation Natural products Oxidative Stress Reactive oxygen species Nrf2 NLRP3 flavonoids NF-kappaB

Scientific Rationale and Application Assessment of Olive Leaf Extract in Skin Redness Care

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

vasodilation Sensory nerve activation

Mechanisms of Action, Representative Compounds, and Research Applications of Senolytics

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Senolytics SASP SCAP Navitoclax cellular senescence senescence-associated secretory phenotype dasatinib quercetin fisetin

Antidiabetic Mechanisms, Representative Bioactive Compounds, and Research Applications of Natural Products

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Natural products diabetes mellitus Oxidative Stress Insulin Resistance gut microbiota drug screening Pancreatic β cells Hepatic Gluconeogenesis Glucose Uptake

Regulatory Mechanisms of Aging-Related Nutrient Sensing, Inflammation, and Homeostatic Signaling Pathways

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Autophagy Aging mTOR AMPK senescence-associated secretory phenotype IIS IGF-1 Sirtuins

Molecular Mechanisms by Which Natural Products Regulate Adipose Browning

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Natural products AMPK adipose browning white adipose tissue UCP1 PGC-1α Hyperforin non-shivering thermogenesis

Glycosidic Bond Structure and Cleavage Mechanisms—Chemical and Enzymatic Cleavage of O-, N-, S-, and C-Glycosides

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

O-glycosides C-glycosides Glycosides

Citations of This Product

How to Cite Aladdin Scientific Products? Citations Search

Calculateurs de solution

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Avis

Need help choosing the grade?

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Luteolin - Moligand™, 10mM in DMSO , Agonist of TAS2R14;Agonist of TAS2R39, CAS No.491-70-3, Agonist of TAS2R14;Agonist of TAS2R39

Storage & shipping

Quality documents

Literature proof

Vue d’ensemble

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Avis des clients

📚 Citations by Application

Need help choosing the grade?

Luteolin - Moligand™, 10mM in DMSO , Agonist of TAS2R14;Agonist of TAS2R39, CAS No.491-70-3, Agonist of TAS2R14;Agonist of TAS2R39

Storage & shipping

Quality documents

Literature proof

Vue d’ensemble

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Avis des clients

📚 Citations by Application

Need help choosing the grade?

View related series