LY 311727 - ≥97% , CAS No.164083-84-5

CAS: 164083-84-5 Cat. No.: L341884 Formule: C22H27N2O5P Poids moléculaire: 430.43
DISPONIBLE À COMMANDE
GRADE & PURITY ≥97%
Synonyms
(3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol-5-yl]oxy}propyl)phosphonic acid | HY-107393 | NCGC00370857-01 | DTXSID80167706 | BDBM23771 | Ly 311727 | OPWQYOUZRHDKBR-UHFFFAOYSA-N | Phosphonic acid, (3-((3-(2-amino-2-oxoethyl)-2-ethyl-1-(phenylmethyl)
Storage
Store at 2-8°C
Shipped In
Wet ice
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Size
Allemagne (EU)
USA*
Price
Qty
10mg
L341884-10mg
Sur commande · 8–12 semaines
302,75€
25mg
L341884-25mg
Sur commande · 8–12 semaines
605,60€
100mg
L341884-100mg
Sur commande · 8–12 semaines
1 936,71€
Enter a quantity for the sizes you want to add.
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Why this grade

≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Vue d’ensemble

LY 311727 is a specific group II sPLA2 (phospholipase A2 (PLA2)) inhibitor which has been reported to attenuate VEGF-mediated platelet-activating factor (PAF) synthesis in HUVEC and BAEC cells.

Specifications

Synonymes
(3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol-5-yl]oxy}propyl)phosphonic acid | HY-107393 | NCGC00370857-01 | DTXSID80167706 | BDBM23771 | Ly 311727 | OPWQYOUZRHDKBR-UHFFFAOYSA-N | Phosphonic acid, (3-((3-(2-amino-2-oxoethyl)-2-ethyl-1-(phenylmethyl)
Spécifications et pureté
≥97%
Conditions de stockage de stockage
Store at 2-8°C
Expédié en
Wet ice
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Type d'action
INHIBITOR
Pureté
≥97%
Noms et identifiants
Sourires canoniquesCCC1=C(C2=C(N1CC3=CC=CC=C3)C=CC(=C2)OCCCP(=O)(O)O)CC(=O)N
IUPAC Name3-[3-(2-amino-2-oxoethyl)-1-benzyl-2-ethylindol-5-yl]oxypropylphosphonic acid
InChIKeyOPWQYOUZRHDKBR-UHFFFAOYSA-N
INCHI1S/C22H27N2O5P/c1-2-20-19(14-22(23)25)18-13-17(29-11-6-12-30(26,27)28)9-10-21(18)24(20)15-16-7-4-3-5-8-16/h3-5,7-10,13H,2,6,11-12,14-15H2,1H3,(H2,23,25)(H2,26,27,28)
Isomères SMILES CCC1=C(C2=C(N1CC3=CC=CC=C3)C=CC(=C2)OCCCP(=O)(O)O)CC(=O)N
WGK Allemagne 3
Poids moléculaire 430.43
Reaxy-Rn 7607479
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7607479&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClasseIndoles and derivatives
SubclassN-alkylindoles
Intermediate Tree Nodes Not available
Direct ParentN-alkylindoles
Alternative Parents 3-alkylindoles  Alkyl aryl ethers  Substituted pyrroles  Benzene and substituted derivatives  Organic phosphonic acids  Heteroaromatic compounds  Primary carboxylic acid amides  Azacyclic compounds  Organopnictogen compounds  Organophosphorus compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents N-alkylindole - 3-alkylindole - Indole - Alkyl aryl ether - Monocyclic benzene moiety - Benzenoid - Substituted pyrrole - Organophosphonic acid - Organophosphonic acid derivative - Heteroaromatic compound - Pyrrole - Carboxamide group - Primary carboxylic acid amide - Ether - Carboxylic acid derivative - Azacycle - Organophosphorus compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic nitrogen compound - Carbonyl group - Organic oxygen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as n-alkylindoles. These are compounds containing an indole moiety that carries an alkyl chain at the 1-position.
External Descriptors Not available
Structure 3D
Modèle de structure chimique interactif





Cibles associées (humaines)
PLA2G2A Tchem Phospholipase A2, membrane associated (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PLA2G2A Tchem Phospholipase A2 group IIA (1079 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cibles associées (non humaines)
PLA2G1B Phospholipase A2 group 1B (227 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Phospholipase A2 (Bee) (126 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cavia porcellus (23802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Phospholipase A2, acidic (39 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mécanismes d'action
Certificats (CoA, COO, BSE/TSE et tableau d'analyse)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propriétés chimiques et physiques
SolubilitéSoluble in DMSO (100 mM), and 1eq. NaOH (100 mM).
Indice de réfractionn20D1.62 (Predicted)
Poids moléculaire430.400 g/mol
XLogP31.700
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count10
Exact Mass430.166 Da
Monoisotopic Mass430.166 Da
Topological Polar Surface Area115.000 Ų
Heavy Atom Count30
Formal Charge0
Complexity606.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculateurs de solution
Avis

Avis des clients

Foire aux questions

What is the purity of this product?
This product is supplied at ≥97% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 164083-84-5, the molecular formula is C22H27N2O5P, and the molecular weight is 430.43 g/mol. InChIKey OPWQYOUZRHDKBR-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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