m-PEG-NHS ester - MW5000 , CAS No.92451-01-9

CAS: 92451-01-9 Cat. No.: M658882 Formule: (C₂H₄O)nC₇H₉NO₅ Poids moléculaire: 293.27 PubChem CID: 71312614

GRADE & PURITY MW5000

Synonyms

Methoxypolyethylene glycol 5,000 acetic acid N-succinimidyl ester | mono-Methyl polyethylene glycol 5′000 acetic acid N-succinimidyl ester | Succinimidyl ester of carboxymethyl-PEG | mPEG-SC (MW 5000) | mPEG-Succinimidyl ester (MW 5000)

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Vue d’ensemble

The m-PEG-NHS ester (MW 5000) is a PROTAC linker belonging to the PEG class. It can be used to synthesize PROTAC molecules

m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Appearance:Solid

IC50& Target:PEGs Alkyl/ether

In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. MCE

Biological Activity:m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Specifications

Synonymes

Methoxypolyethylene glycol 5,000 acetic acid N-succinimidyl ester | mono-Methyl polyethylene glycol 5′000 acetic acid N-succinimidyl ester | Succinimidyl ester of carboxymethyl-PEG | mPEG-SC (MW 5000) | mPEG-Succinimidyl ester (MW 5000)

Spécifications et pureté

MW5000

Conditions de stockage de stockage

Protected from light,Store at -20°C,Argon charged

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Noms et identifiants

• Sourires canoniques: COCCO.C1CC(=O)N(C1=O)OC(=O)COCCO
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 2-(2-hydroxyethoxy)acetate;2-methoxyethanol
• InChIKey: NYXRHTOXAYVBMV-UHFFFAOYSA-N
• INCHI: 1S/C8H11NO6.C3H8O2/c10-3-4-14-5-8(13)15-9-6(11)1-2-7(9)12;1-5-3-2-4/h10H,1-5H2;4H,2-3H2,1H3
• Isomères SMILES: COCCO.C1CC(=O)N(C1=O)OC(=O)COCCO
• WGK Allemagne: 3
• PubChem CID: 71312614
• Poids moléculaire: 293.27

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Pyrrolidines
      • Subclass Pyrrolidones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Pyrrolidines
• Subclass: Pyrrolidones
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyrrolidine-2-ones
• Alternative Parents: Dicarboximides Lactams Monocarboxylic acids and derivatives Dialkyl ethers Azacyclic compounds Primary alcohols Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Not available
• Substituents: 2-pyrrolidone - Dicarboximide - Lactam - Carboxylic acid derivative - Dialkyl ether - Ether - Monocarboxylic acid or derivatives - Azacycle - Organonitrogen compound - Alcohol - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Organooxygen compound - Primary alcohol - Organic oxide - Hydrocarbon derivative - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as pyrrolidine-2-ones. These are pyrrolidines which bear a C=O group at position 2 of the pyrrolidine ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriétés chimiques et physiques

• Sensibilité: Light Sensitive；Moisture Sensitive

Foire aux questions

How should this product be stored?

Store at ?20 °C, protected from light, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 92451-01-9, the molecular formula is (C2H4O)nC7H9NO5, and the molecular weight is 293.27 g/mol. InChIKey NYXRHTOXAYVBMV-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.