≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Vue d’ensemble
M4K2234 (compound 26b) is an ALK2 inhibitor. M4K2234 inhibits ALK2 and ALK5 with IC 50 s of 5 and 2144 nM, respectively. M4K2234 can be used as a chemical probe for ALK1 and ALK2 protein kinases. M4K2234 can be used for the research of cancer
In Vitro
M4K2234 (0-5 μM) shows inhibitory effects against WT and DIPG-linked mutant forms of ALK2 with IC 50 s of 5, 3, 6 and 6 nM for WT, G328V, R206H and R258G, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
1.19 Pharmacokinetic Properties of M4K2234 in Mice . Mice PO 3 mg/kg C max (ng/mL) 1650 AUC inf (ng·h/mL) 4630 t 1/2 (h) 2.61 MCE has not independently confirmed the accuracy of these methods. They are for reference only.
M4K2234 (compound 26b) is an ALK2 inhibitor. M4K2234 inhibits ALK2 and ALK5 with IC 50 s of 5 and 2144 nM, respectively. M4K2234 can be used as a chemical probe for ALK1 and ALK2 protein kinases. M4K2234 can be used for the research of cancer.
Conditions de stockage de stockage
Store at -20°C
Expédié en
Ice chest + Ice pads
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Type d'action
INHIBITOR
Pureté
≥98%
Noms et identifiants
Poids moléculaire
462.56
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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