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Récepteur activé par les proliférateurs de peroxysomes
MA-0204 - ≥98% , CAS No.2095128-17-7

MA-0204 - ≥98% , CAS No.2095128-17-7

Name: MA-0204 - ≥98% , CAS No.2095128-17-7
SKU: M412414
Availability: InStock

CAS: 2095128-17-7 Cat. No.: M412414 Formule: C₂₅H₂₇F₃N₂O₄ Poids moléculaire: 476.49

COA

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MA-0204 - ≥98% CAS No(2095128-17-7) by Aladdin Scientific

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DISPONIBLE À COMMANDE

GRADE & PURITY ≥98%

Synonyms

(R)-3-methyl-6-(2-((5-methyl-2-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)methyl)phenoxy)hexanoic acid

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble Specifications Noms et identifiants Documentation Advanced Data Structure 3D Cibles associées (humaines) Cibles associées (non humaines) Mécanismes d'action Certificats (CoA, COO, BSE/TSE et tableau d'analyse) Propriétés chimiques et physiques Calculateurs de solution Avis

🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Vue d’ensemble

Information

MA-0204 is a potent, highly selective and orally available modulator of peroxisome proliferator activated receptor δ (PPARδ) with EC50 of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. MA-0204 is used as a potential treatment for Duchene Muscular Dystrophy (DMD).

Specifications

Synonymes

(R)-3-methyl-6-(2-((5-methyl-2-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)methyl)phenoxy)hexanoic acid

Spécifications et pureté

≥98%

Mécanismes biochimiques et physiologiques

MA-0204 is a potent, highly selective and orally available modulator of peroxisome proliferator activated receptor δ (PPARδ) with\xa0EC50 of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. MA-0204 is used as a potential treatment fo

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

MODULATOR

Pureté

≥98%

Noms et identifiants

Pubchem Sid	528765413
Sourires canoniques	CC1=CN=C(N1CC2=CC=CC=C2OCCCC(C)CC(=O)O)C3=CC=C(C=C3)OC(F)(F)F
IUPAC Name	(3R)-3-methyl-6-[2-[[5-methyl-2-[4-(trifluoromethoxy)phenyl]imidazol-1-yl]methyl]phenoxy]hexanoic acid
InChIKey	GYNMVDMBFKGCCR-QGZVFWFLSA-N
INCHI	1S/C25H27F3N2O4/c1-17(14-23(31)32)6-5-13-33-22-8-4-3-7-20(22)16-30-18(2)15-29-24(30)19-9-11-21(12-10-19)34-25(26,27)28/h3-4,7-12,15,17H,5-6,13-14,16H2,1-2H3,(H,31,32)/t17-/m1/s1
Isomères SMILES	CC1=CN=C(N1CC2=CC=CC=C2OCCC[C@@H](C)CC(=O)O)C3=CC=C(C=C3)OC(F)(F)F
Poids moléculaire	476.49
Reaxy-Rn	41991544
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=41991544&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Structure 3D

Cibles associées (humaines)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (1 Activities)

Discover Target: KCNH2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PPARD Tchem Peroxisome proliferator-activated receptor delta (1 Activities)

Discover Target: PPARD

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PGR Tclin Progesterone receptor (8562 Activities)

Discover Target: PGR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)

Discover Target: PPARG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PPARA Tclin Peroxisome proliferator-activated receptor alpha (9197 Activities)

Discover Target: PPARA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

Discover Target: CYP2C9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cibles associées (non humaines)

Ppard Peroxisome proliferator-activated receptor delta (358 Activities)

Discover Target: Ppard

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mécanismes d'action

Certificats (CoA, COO, BSE/TSE et tableau d'analyse)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot Number	Certificate Type	Date	Article
G2415454	Certificate of Analysis	Apr 01, 2024	M412414
G2415455	Certificate of Analysis	Apr 01, 2024	M412414
G2415457	Certificate of Analysis	Apr 01, 2024	M412414
G2415458	Certificate of Analysis	Apr 01, 2024	M412414
G2415459	Certificate of Analysis	Apr 01, 2024	M412414
G2415460	Certificate of Analysis	Apr 01, 2024	M412414
G2415461	Certificate of Analysis	Apr 01, 2024	M412414
G2415462	Certificate of Analysis	Apr 01, 2024	M412414
G2415463	Certificate of Analysis	Apr 01, 2024	M412414

Propriétés chimiques et physiques

Poids moléculaire	476.500 g/mol
XLogP3	5.800
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	11
Exact Mass	476.192 Da
Monoisotopic Mass	476.192 Da
Topological Polar Surface Area	73.600 Å²
Heavy Atom Count	34
Formal Charge	0
Complexity	628.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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Avis

Bulk & Custom Packaging Need larger quantities or custom specifications? Contact our team for a tailored quote.

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