MAC glucuronide linker-2 - Moligand™, ≥99% , CAS No.229977-57-5

CAS: 229977-57-5 Cat. No.: M649497 Formule: C₂₀H₂₅NO₁₁ Poids moléculaire: 455.42

GRADE & PURITY Moligand™, ≥99%

Synonyms

Methyl 2-Amino-4-(hydroxymethyl)phenyl 2,3,4-tri-O-acetyl-β-D-glucuronate | 2-Amino-4-(hydroxymethyl)phenyl 2,3,4-tri-O-acetyl-β-D-glucuronic Acid Methyl Ester

Storage

Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

Vue d’ensemble

MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

Form:Solid

IC50& Target:Cleavable Glycosidase Cleavable

Specifications

Synonymes

Methyl 2-Amino-4-(hydroxymethyl)phenyl 2,3,4-tri-O-acetyl-β-D-glucuronate | 2-Amino-4-(hydroxymethyl)phenyl 2,3,4-tri-O-acetyl-β-D-glucuronic Acid Methyl Ester

Spécifications et pureté

Moligand™, ≥99%

Mécanismes biochimiques et physiologiques

MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Conditions de stockage de stockage

Store at -20°C,Argon charged,Desiccated

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Pureté

≥99%

Noms et identifiants

• Sourires canoniques: CC(=O)OC1C(C(OC(C1OC(=O)C)OC2=C(C=C(C=C2)CO)N)C(=O)OC)OC(=O)C
• IUPAC Name: methyl (2S,3S,4S,5R,6S)-3,4,5-triacetyloxy-6-[2-amino-4-(hydroxymethyl)phenoxy]oxane-2-carboxylate
• InChIKey: ZAZPQJAJSIUIEY-KVIJGQROSA-N
• INCHI: 1S/C20H25NO11/c1-9(23)28-15-16(29-10(2)24)18(30-11(3)25)20(32-17(15)19(26)27-4)31-14-6-5-12(8-22)7-13(14)21/h5-7,15-18,20,22H,8,21H2,1-4H3/t15-,16-,17-,18+,20+/m0/s1
• Isomères SMILES: CC(=O)O[C@H]1[C@@H]([C@H](O[C@H]([C@@H]1OC(=O)C)OC2=C(C=C(C=C2)CO)N)C(=O)OC)OC(=O)C
• Poids moléculaire: 455.42

Propriétés chimiques et physiques

• Solubilité: DMSO : 200 mg/mL (439.16 mM; Need ultrasonic)
• Sensibilité: Moisture sensitive，Air sensitive，Heat sensitive
• Point de fusion (°C): 138.0-142.0 °C
• Poids moléculaire: 455.400 g/mol
• XLogP3: -0.100
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 11
• Exact Mass: 455.143 Da
• Monoisotopic Mass: 455.143 Da
• Topological Polar Surface Area: 170.000 Ų
• Heavy Atom Count: 32
• Formal Charge: 0
• Complexity: 699.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 5
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Foire aux questions

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C, desiccated, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 229977-57-5, the molecular formula is C20H25NO11, and the molecular weight is 455.42 g/mol. InChIKey ZAZPQJAJSIUIEY-KVIJGQROSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.