MAZ51 - Moligand™, ≥98% , CAS No.163655-37-6

CAS: 163655-37-6 Cat. No.: M338455 Formule: C₂₁H₁₈N₂O Poids moléculaire: 314.38 Numéro CE: 634-088-2

GRADE & PURITY Moligand™, ≥98%

Synonyms

3-(4-Dimethylaminonaphthalen-1-ylmethylene)-1,3-dihydroindol-2-one | BCP31595 | SCHEMBL3374614 | VFCXONOPGCDDBQ-UHFFFAOYSA-N | 3-[[4-(dimethylamino)naphthalen-1-yl]methylidene]-1H-indol-2-one | 3-[[4-(dimethylamino)-1-naphthalenyl]methylidene]-1H-indol-2-

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Vue d’ensemble

MAZ51 inhibits vascular endothelial cell growth factor-C (VEGF-C)-induced intracellular phosphorylation of Flt-4 (VEGFR-3) (IC|50|= 1 μM). MAZ51 is an inhibitor of Flt-4.

Specifications

Synonymes

3-(4-Dimethylaminonaphthalen-1-ylmethylene)-1,3-dihydroindol-2-one | BCP31595 | SCHEMBL3374614 | VFCXONOPGCDDBQ-UHFFFAOYSA-N | 3-[[4-(dimethylamino)naphthalen-1-yl]methylidene]-1H-indol-2-one | 3-[[4-(dimethylamino)-1-naphthalenyl]methylidene]-1H-indol-2-

Spécifications et pureté

Moligand™, ≥98%

Conditions de stockage de stockage

Store at -20°C,Argon charged

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Type d'action

INHIBITOR

Pureté

≥98%

Propriétés du produit

• pKa: pKa: 12.78 (Predicted), pKa: 4.42 (Predicted)

Noms et identifiants

• Pubchem Sid: 504769911
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504769911
• Sourires canoniques: CN(C)C1=CC=C(C2=CC=CC=C21)C=C3C4=CC=CC=C4NC3=O
• IUPAC Name: 3-[[4-(dimethylamino)naphthalen-1-yl]methylidene]-1H-indol-2-one
• InChIKey: VFCXONOPGCDDBQ-UHFFFAOYSA-N
• INCHI: 1S/C21H18N2O/c1-23(2)20-12-11-14(15-7-3-4-9-17(15)20)13-18-16-8-5-6-10-19(16)22-21(18)24/h3-13H,1-2H3,(H,22,24)
• Isomères SMILES: CN(C)C1=CC=C(C2=CC=CC=C21)C=C3C4=CC=CC=C4NC3=O
• WGK Allemagne: 3
• Poids moléculaire: 314.38
• Reaxy-Rn: 27760008
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=27760008&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Naphthalenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Naphthalenes
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Naphthalenes
• Alternative Parents: Indolines Dialkylarylamines Secondary carboxylic acid amides Lactams Amino acids and derivatives Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Naphthalene - Indole or derivatives - Dihydroindole - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Amino acid or derivatives - Carboxamide group - Lactam - Secondary carboxylic acid amide - Tertiary amine - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Amine - Organic oxygen compound - Carbonyl group - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as naphthalenes. These are compounds containing a naphthalene moiety, which consists of two fused benzene rings.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriétés chimiques et physiques

• Solubilité: Soluble in DMSO (11 mg/ml).
• Sensibilité: Light sensitive
• Indice de réfraction: n20D1.73 (Predicted)
• Point d'ébullition (°C): 553.92° C at 760 mmHg (Predicted)
• Point de fusion (°C): 222.83° C (Predicted)
• Poids moléculaire: 314.400 g/mol
• XLogP3: 4.300
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 314.142 Da
• Monoisotopic Mass: 314.142 Da
• Topological Polar Surface Area: 32.299 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 512.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 1
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1

Foire aux questions

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 163655-37-6, the molecular formula is C21H18N2O, and the molecular weight is 314.38 g/mol. InChIKey VFCXONOPGCDDBQ-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.