Mc-MMAE - ≥96% , CAS No.863971-24-8

CAS: 863971-24-8 Cat. No.: M648597 Molecular Weight: 911.18
AVAILABLE TO ORDER
GRADE & PURITY ≥96%
Synonyms
Maleimidocaproyl-monomethylauristatin E
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
M648597-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
5mg
M648597-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$137.90
25mg
M648597-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$379.90
100mg
M648597-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$987.90
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Why this grade

≥96% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a agent-linker conjugate for ADC.

In Vitro

Synthesis of maleimidocaproyl-MMAE (mc-MMAE) requires the addition of maleimidocaproic acid to a solution of MMAE in dichloromethane followed by the addition of diethyl cyanophosphonate and diisopropylethylamine. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Auristatin

Specifications

Synonyms
Maleimidocaproyl-monomethylauristatin E
Specifications & Purity
≥96%
Biochemical and Physiological Mechanisms
Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a agent-linker conjugate for ADC.
Storage
Store at 2-8°C, Argon charged
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥96%
Names and Identifiers
Molecular Weight 911.18

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot NumberCertificate TypeDateItem
K2519478Certificate of AnalysisNov 26, 2025 M648597
K2519479Certificate of AnalysisNov 26, 2025 M648597
K2519481Certificate of AnalysisNov 26, 2025 M648597
K2519469Certificate of AnalysisNov 25, 2025 M648597
K2519470Certificate of AnalysisNov 25, 2025 M648597
K2519476Certificate of AnalysisNov 25, 2025 M648597
K2519477Certificate of AnalysisNov 25, 2025 M648597
Chemical and Physical Properties
SolubilityDMSO : 180 mg/mL (197.55 mM; Need ultrasonic) H2O : <0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Solution Calculators
Reviews

Customer Reviews

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