MDL 72222 - ≥99% , CAS No.40796-97-2
Selective 5-HT 3 receptor antagonist
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Selective 5-HT 3 receptor antagonist
Application:
It is most often used to study the role of SR-3. Studies suggest the blockade of SR-3 with may ameliorate beta-amyloid protein-induced neurotoxicity by interfering with the increase of Ca2+, and then by inhibiting glutamate release, generation of reactive oxygen species and caspase-3 activity. It is also used in the study of dopamine elevation in rats due to cocaine and amphetamine consumption.
| CAS | 40796-97-2 |
|---|---|
| Synonymes | Bemesetron (USAN/INN) | BEMESETRON [USAN] | Tocris-0640 | Tox21_110293_1 | NCGC00186619-01 | CAS-40796-97-2 | BEMESETRON [INN] | AKOS040741307 | Benzoic acid, 3,5-dichloro-, (3-endo)-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester | D03073 | Lopac-T-8160 | NCG |
| Spécifications et pureté | ≥99% |
| Conditions de stockage de stockage | Store at -20°C |
| Expédié en | Ice chest + Ice pads |
| Product Description | Application: It is most often used to study the role of SR-3. Studies suggest the blockade of SR-3 with may ameliorate beta-amyloid protein-induced neurotoxicity by interfering with the increase of Ca2+, and then by inhibiting glutamate release, generation of reactive oxygen species and caspase-3 activity. It is also used in the study of dopamine elevation in rats due to cocaine and amphetamine consumption. |
| Pubchem Sid | 504759821 |
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504759821 |
| Solubilité | Soluble in ethanol to 100 mM and in DMSO to 100 mM |
| Numéro CE | 637-013-1 |
| PubChem CID | 671690 |
| Formule moléculaire | C15H17Cl2NO2 |