Determine the necessary mass, volume, or concentration for preparing a solution.
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
MES Sodium Salt (Sodium 2-Morpholinoethanesulfonate) is a zwitterionic N-substituted aminosulfonic acid known as a Good’s buffer, active in the pH range 6-8 with a pKa of 6.10 at 25°C. With a pKa value near physiological pH, it is not absorbed through cell membranes, and it is essentially transparent to UV light. MES is used as a running buffer for resolving very small proteins (ex: 13 kDa) on bis-tris gels. Also used in cation-exchange chromatography and as a biological buffer in plant cell cultures. MES solutions can be prepared to the desired pH by titrating the free acid with sodium hydroxide.
A buffering agent used in biological and biochemical research including plant cell culture.
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Classe | Oxazinanes |
| Subclass | Morpholines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Morpholines |
| Alternative Parents | Sulfonyls Organosulfonic acids Alkanesulfonic acids Trialkylamines Oxacyclic compounds Dialkyl ethers Azacyclic compounds Organopnictogen compounds Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aliphatic heteromonocyclic compounds |
| Substituents | Morpholine - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Organosulfonic acid - Sulfonyl - Alkanesulfonic acid - Tertiary amine - Tertiary aliphatic amine - Dialkyl ether - Ether - Oxacycle - Azacycle - Organic alkali metal salt - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Amine - Organic nitrogen compound - Organic zwitterion - Organic salt - Organic sodium salt - Aliphatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as morpholines. These are organic compounds containing a morpholine moiety, which consists of a six-member aliphatic saturated ring with the formula C4H9NO, where the oxygen and nitrogen atoms lie at positions 1 and 4, respectively. |
| External Descriptors | organic sodium salt |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Article |
|---|---|---|---|
| Certificate of Analysis | Jun 03, 2026 | M105136 | |
| Certificate of Analysis | Jun 03, 2026 | M105136 | |
| Certificate of Analysis | Jun 03, 2026 | M105136 | |
| Certificate of Analysis | Jun 03, 2026 | M105136 | |
| Certificate of Analysis | Jun 03, 2026 | M105136 | |
| Certificate of Analysis | Oct 21, 2025 | M105136 | |
| Certificate of Analysis | Oct 21, 2025 | M105136 | |
| Certificate of Analysis | Oct 21, 2025 | M105136 | |
| Certificate of Analysis | Oct 21, 2025 | M105136 | |
| Certificate of Analysis | Oct 21, 2025 | M105136 | |
| Certificate of Analysis | Oct 21, 2025 | M105136 | |
| Certificate of Analysis | Oct 21, 2025 | M105136 | |
| Certificate of Analysis | Apr 11, 2025 | M105136 | |
| Certificate of Analysis | Apr 11, 2025 | M105136 | |
| Certificate of Analysis | Apr 11, 2025 | M105136 | |
| Certificate of Analysis | Apr 11, 2025 | M105136 | |
| Certificate of Analysis | Apr 11, 2025 | M105136 | |
| Certificate of Analysis | Apr 11, 2025 | M105136 | |
| Certificate of Analysis | Oct 12, 2024 | M105136 | |
| Certificate of Analysis | Sep 03, 2024 | M105136 | |
| Certificate of Analysis | Sep 03, 2024 | M105136 | |
| Certificate of Analysis | Sep 03, 2024 | M105136 | |
| Certificate of Analysis | Mar 17, 2022 | M105136 | |
| Certificate of Analysis | Mar 17, 2022 | M105136 | |
| Certificate of Analysis | Mar 17, 2022 | M105136 | |
| Certificate of Analysis | Mar 17, 2022 | M105136 | |
| Certificate of Analysis | Mar 17, 2022 | M105136 | |
| Certificate of Analysis | Mar 17, 2022 | M105136 | |
| Certificate of Analysis | Mar 17, 2022 | M105136 | |
| Certificate of Analysis | May 31, 2021 | M105136 |
| Solubilité | Solvent:water, Max Conc. mg/mL: 21.72, Max Conc. mM: 100 |
|---|---|
| Sensibilité | Hygroscopic;heat sensitive |
| Poids moléculaire | 217.220 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 3 |
| Exact Mass | 217.038 Da |
| Monoisotopic Mass | 217.038 Da |
| Topological Polar Surface Area | 78.100 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 219.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |