ML252 - ≥99% , CAS No.1392494-64-2

CAS: 1392494-64-2 Cat. No.: M1438161 Formule: C₂₀H₂₅ClN₂O Poids moléculaire: 344.9 PubChem CID: 53393831

GRADE & PURITY ≥99%

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Vue d’ensemble

ML252 is a selective inhibitor of KCNQ2 (Kv7.2) channel with an IC 50 s of 69 nM, 2.92 μM, 0.12 μM and 0.20 μM for KCNQ2, KCNQ1 (Kv7.1), KCNQ2/Q3 and KCNQ4, respectively. ML252 also inhibits Cytochrome P450 with IC 50 s of 6.1 nM ( CYP1A2 ), 18.9 nM ( CYP2C9 ), 3.9 nM ( CYP3A4 ), 19.9 nM ( CYP2D6 ), respectively. ML252 shows highly brain penetrant.

Specifications

Spécifications et pureté

≥99%

Conditions de stockage de stockage

Protected from light,Store at -20°C,Argon charged

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Pureté

≥99%

Noms et identifiants

• Sourires canoniques: CCC(C1=CC=CC=C1)C(=O)NC2=CC=CC=C2N3CCCC3.Cl
• IUPAC Name: (2S)-2-phenyl-N-(2-pyrrolidin-1-ylphenyl)butanamide;hydrochloride
• InChIKey: XBYCQOZNTLUEDX-LMOVPXPDSA-N
• INCHI: 1S/C20H24N2O.ClH/c1-2-17(16-10-4-3-5-11-16)20(23)21-18-12-6-7-13-19(18)22-14-8-9-15-22;/h3-7,10-13,17H,2,8-9,14-15H2,1H3,(H,21,23);1H/t17-;/m0./s1
• Isomères SMILES: CC[C@@H](C1=CC=CC=C1)C(=O)NC2=CC=CC=C2N3CCCC3.Cl
• WGK Allemagne: 3
• PubChem CID: 53393831
• Poids moléculaire: 344.9

Foire aux questions

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, protected from light, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1392494-64-2, the molecular formula is C20H25ClN2O, and the molecular weight is 344.9 g/mol. InChIKey XBYCQOZNTLUEDX-LMOVPXPDSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.