≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Vue d’ensemble
MM 419447, a linaclotide metabolite, is a guanylate cyclase-C agonist. MM 419447 has the potential for the research of the irritable bowel syndrome with constipation (IBS-C).
In Vitro
MM 419447 exhibits high-affinity binding to T84 cells, resulting in a significant, concentration-dependent accumulation of intracellular cyclic guanosine-39,59-monophosphate (cGMP). MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MM 419447 (10 mg/kg; p.o.) treatment shows the C max , AUC 0-6 and t 1/2 values of 27 ng/mL, ≤ 29.7 ng h/mL and 0.33 hours, respectively MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Female Sprague-Dawley rats Dosage: 10 mg/kg Administration: P.o. (Pharmacokinetic Analysis) Result: The C max , AUC 0-6 and T max were 27 ng/mL, ≤ 29.7 ng h/mL and 0.33 hours, respectively.
Form:Solid
Specifications
Spécifications et pureté
≥99%
Mécanismes biochimiques et physiologiques
MM 419447, a linaclotide metabolite, is a guanylate cyclase-C agonist. MM 419447 has the potential for the research of the irritable bowel syndrome with constipation (IBS-C).
Conditions de stockage de stockage
Desiccated,Store at -80°C
Expédié en
Dry ice packs + Cold packs
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Type d'action
AGONIST
Pureté
≥99%
Noms et identifiants
Poids moléculaire
1363.56
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Certificats (CoA, COO, BSE/TSE et tableau d'analyse)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propriétés chimiques et physiques
Solubilité
DMSO : 100 mg/mL (73.34 mM; Need ultrasonic)
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Foire aux questions
What is the purity of this product?
This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?80 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.
How is this product shipped?
This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 1092457-78-7, the molecular formula is C50H70N14O19S6, and the molecular weight is 1363.56 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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