MU1210 , CAS No.2275601-87-9

CAS: 2275601-87-9 Cat. No.: M1425991 PubChem CID: 155891794

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

MU1210 (compound 12f) is an inhibitor of CDC-like kinases Clk1 , Clk2 , and Clk4 (with IC 50 values of 8, 20, and 12 nM respectively), with IC 50 for HIPK1 and DYRK2 are 187 and 1309 nM. MU1210 also has favorable pharmacokinetic characteristics (in mice, 10 mg/kg, intraperitoneal injection: C max =1.24 μM, T 1/2 =58 minutes; no acute toxicity observed).

Specifications

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Noms et identifiants

Sourires canoniques

CN1C=C(C=N1)C2=NC3=C(C=C2)OC=C3C4=CC=CC(=C4)C5=CC=NC=C5

IUPAC Name

5-(1-methylpyrazol-4-yl)-3-(3-pyridin-4-ylphenyl)furo[3,2-b]pyridine

InChIKey

HEAGNKNMQVIVMM-UHFFFAOYSA-N

INCHI

1S/C22H16N4O/c1-26-13-18(12-24-26)20-5-6-21-22(25-20)19(14-27-21)17-4-2-3-16(11-17)15-7-9-23-10-8-15/h2-14H,1H3

Isomères SMILES

CN1C=C(C=N1)C2=NC3=C(C=C2)OC=C3C4=CC=CC(=C4)C5=CC=NC=C5

PubChem CID

155891794